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Levobetaxolol
Known as:
(S)-betaxolol
The S-isomer of betaxolol, a selective beta-1 adrenergic receptor antagonist with anti-glaucoma activity and devoid of intrinsic sympathomimetic…
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National Institutes of Health
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1 relation
levobetaxolol hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Rapid network meta-analysis using data from the U.S. Food and Drug Administration approval packages and ClinicalTrials.gov – a case study on first-line medications for glaucoma
Lin Wang
2018
Corpus ID: 196574163
Review
2015
Review
2015
Current Options for Treatment of Glaucoma in Pediatrics
Fahad I Al-Saikhan
2015
Corpus ID: 53556628
Introduction: The treatment of pediatric glaucoma is normally complicated in this population owing to the visual immaturity of…
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2009
2009
Application of kinetic resolution using HCS as chiral auxiliary: novel synthesis of beta-blockers (S)-betaxolol and (S)-metoprolol.
Jing-Yu Zhang
,
Hong-min Liu
,
Xiaojun Wang
,
Pei Wang
,
Jiaxin Zheng
Chirality
2009
Corpus ID: 23587984
Optically pure (S)-betaxolol and (S)-metoprolol were prepared with an extremely facile and practical method using kinetic…
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2004
2004
Binding Affinities of Ocular Hypotensive β-Blockers Levobetaxolol, Levobunolol, and Timolol at Endogenous Guinea Pig β-Adrenoceptors
N. Sharif
,
S. Xu
2004
Corpus ID: 84238422
The current study determined the relative affinities and selectivities of numerous β-adrenoceptor antagonists at the endogenous…
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2004
2004
Binding affinities of ocular hypotensive beta-blockers levobetaxolol, levobunolol, and timolol at endogenous guinea pig beta-adrenoceptors.
N. Sharif
,
S. Xu
Journal of Ocular Pharmacology and Therapeutics
2004
Corpus ID: 42258547
The current study determined the relative affinities and selectivities of numerous beta-adrenoceptor antagonists at the…
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2003
2003
Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs
J. Melena
,
N. Osborne
Graefe's Archive for Clinical and Experimental…
2003
Corpus ID: 1529820
Abstract.BackgroundFree radical production seems to be involved in the pathogenesis of a number of ocular diseases. Certain…
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2002
2002
Levobetaxolol-induced Up-regulation of retinal bFGF and CNTF mRNAs and preservation of retinal function against a photic-induced retinopathy.
N. Agarwal
,
E. Martin
,
+5 authors
R. Collier
Experimental Eye Research
2002
Corpus ID: 22897486
Betaxolol (racemic), a beta-adrenoceptor antagonist that is used to lower intraocular pressure in the treatment of glaucoma, has…
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2002
2002
Adenylyl cyclase activity mediated by beta-adrenoceptors in immortalized human trabecular meshwork and non-pigmented ciliary epithelial cells.
J. Crider
,
N. Sharif
Journal of Ocular Pharmacology and Therapeutics
2002
Corpus ID: 23368597
Non-pigmented ciliary epithelial (NPE) and trabecular meshwork (TM) cells are important in maintaining normal aqueous humor…
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2001
2001
Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes.
N. Sharif
,
S. Xu
,
J. Crider
,
M. McLaughlin
,
T. Davis
Journal of Ocular Pharmacology and Therapeutics
2001
Corpus ID: 20221684
The pharmacological characteristics of levobetaxolol, a single active isomer of betaxolol, were determined and compared with…
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2000
2000
Betaxolol, a beta(1)-adrenoceptor antagonist, reduces Na(+) influx into cortical synaptosomes by direct interaction with Na(+) channels: comparison with other beta-adrenoceptor antagonists.
G. Chidlow
,
J. Melena
,
N. Osborne
British Journal of Pharmacology
2000
Corpus ID: 42364157
Betaxolol, a beta(1)-adrenoceptor antagonist used for the treatment of glaucoma, is known to be neuroprotective in paradigms of…
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