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Leukemogenesis

Known as: Leukemogenesis/Lymphomagenesis, Lymphomagenesis 
The causation (or induction), development, and progression of a leukaemic disease.(On-line Medical Dictionary)
National Institutes of Health

Related topics

Related topics

7 relations
CarcinogenesisFRAT1 geneFRAT1 wt AlleleLymphocyte

Papers overview

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Highly Cited
2002
Highly Cited
2002
DNA Methyltransferase Deficiency Modifies Cancer Susceptibility in Mice Lacking DNA Mismatch Repair
ABSTRACT We have introduced DNA methyltransferase 1 (Dnmt1) mutations into a mouse strain deficient for the Mlh1 protein to study… 
Review
2000
Review
2000
Homeobox genes in leukemogenesis.
Considerable progress has been made in unraveling key pathogenetic steps in human leukemogenesis. In recent years, cytogenetic… 
Highly Cited
1999
Highly Cited
1999
A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with MYC
The Cbfa1/PEBP2αA/AML3 gene plays an essential role in osteogenesis but is also expressed in the T-cell lineage where it has been… 
Highly Cited
1998
Highly Cited
1998
Heterologous promoters fused to BCL6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation.
The BCL6 gene encodes a POZ/Zinc-finger protein, which acts as a sequence-specific transcriptional repressor. It is expressed in… 
Highly Cited
1997
Highly Cited
1997
Frequent mutation of the 5' noncoding region of the BCL-6 gene in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas.
Acquired immunodeficiency syndrome (AIDS)-related non-Hodgkin's lymphomas (AIDS-NHL), a major source of morbidity and mortality… 
Highly Cited
1997
Highly Cited
1997
High-level DNA amplifications are common genetic aberrations in B-cell neoplasms.
Gene amplification is one of the molecular mechanisms resulting in the up-regulation of gene expression. In non-Hodgkin's… 
Highly Cited
1995
Highly Cited
1995
Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis.
Deregulation of c-myc, frequently implicated in oncogenesis, is associated with increased cell proliferation and also cell death… 
Review
1990
Review
1990
Prognostic and biological importance of chromosome findings in acute lymphoblastic leukemia.
Highly Cited
1984
Highly Cited
1984
Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas.
Sixty-one murine leukemia virus-induced lymphomas were examined for evidence of proviral insertions adjacent to known oncogenes… 
Highly Cited
1978
Highly Cited
1978
Abelson virus-induced lymphomagenesis in mice
The salient facts which have emerged from our study of Abelson virus (MuLV-A)lymphomagenesis in mice are that lymphoma induction… 
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