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Leptocyte

Known as: cells target, TARGET CELLS, target cell 
National Institutes of Health

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DEHYDRATED HEREDITARY STOMATOCYTOSIS 2STOMATOCYTOSIS I

Papers overview

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1995
1995
Synergistic inhibition of human cell-mediated cytotoxicity by complement component antisera indicates that target cell lysis may result from an enzymatic cascade involving granzymes and perforin.
A widely accepted theory of lymphocyte-mediated cytotoxicity (CMC) proposes that upon effector cell (EC) and target cell (TC… 
1992
1992
Poly-(ADP-ribose) polymerase partially contributes to target cell death triggered by cytolytic T lymphocytes.
We hypothesized that CTL-induced target cell (TC) death is partially due to processes that follow the DNA damage in target cells… 
1989
1989
Cytotoxic T lymphocyte-induced loss of target cell adhesion and lysis involve common and separate signaling pathways.
Recently, we demonstrated that an early event in the CTL-target cell (TC) interaction is loss of TC adherence to substrate. This… 
Review
1988
Review
1988
Mechanistic, functional and immunopharmacological implications of biochemical studies of antigen receptor-triggered cytolytic T-lymphocyte activation.
Biochemical events that follow the engagement of cytotoxic T lymphocytes (CTL) with an Ag-bearing target cell (TC) or triggering… 
1987
1987
T cell antigen receptor triggered exocytosis in cytotoxic T lymphocytes is inhibited by soluble, but not immobilized monoclonal antibodies to Lyt-2 antigen.
The effect of monoclonal antibodies (mAb) to surface antigens on the T cell antigen receptor (TcR)-triggered exocytosis of… 
1987
1987
Target cell recognition structures in LDCC and ODCC.
Cytotoxic T lymphocyte effector cells specific for a defined class I antigen can kill target cells displaying a wide range of… 
1985
1985
Evidence for an early calcium-independent event in the activation of the human natural killer cell cytolytic mechanism.
In this study, we examined the functional status of human natural killer (NK) cells after their direct interaction with the NK… 
1983
1983
Specific lysis of antigenically irrelevant cells by cytotoxic T lymphocytes upon insertion of appropriate antigens into the target cell plasma membranes.
The importance of the membrane milieu to functional presentation of target cell (TC) antigens to cytotoxic T lymphocytes (CTL… 
Highly Cited
1981
Highly Cited
1981
T lymphocyte-mediated cytolysis. I. A common mechanism for target recognition in specific and lectin-dependent cytolysis.
In this and the accompanying paper we examine the nature of the interactions between effector cells and target cells leading to… 
1980
1980
The Ultrastructure of the Tubular Complex in the Cytoplasm of Cytolytic T Lymphocytes
The DNA synthesis, the cytolytic activity, and the ultrastructure of cytolytic T lymphocytes (CTL) derived from mixed mouse… 
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