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Leptocyte

Known as: cells target, TARGET CELLS, target cell 
National Institutes of Health

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2 relations
DEHYDRATED HEREDITARY STOMATOCYTOSIS 2STOMATOCYTOSIS I

Papers overview

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1995
1995
Fas-mediated cytotoxicity remains intact in perforin and granzyme B antisense transfectants of a human NK-like cell line.
Cell-mediated cytotoxicity (CMC) has traditionally been thought to involve the release of granule components, including perforin… 
1994
1994
Thiol supplier N-acetylcysteine enhances conjugate formation between natural killer cells and K562 or U937 targets but increases the lytic function only against the latter.
1992
1992
Poly-(ADP-ribose) polymerase partially contributes to target cell death triggered by cytolytic T lymphocytes.
We hypothesized that CTL-induced target cell (TC) death is partially due to processes that follow the DNA damage in target cells… 
1989
1989
Cytotoxic T lymphocyte-induced loss of target cell adhesion and lysis involve common and separate signaling pathways.
Recently, we demonstrated that an early event in the CTL-target cell (TC) interaction is loss of TC adherence to substrate. This… 
1988
1988
Target cell directed NK inactivation. Concomitant loss of NK and antibody-dependent cellular cytotoxicity activities.
We investigated the inactivation of human NK cells, a population of large granular lymphocytes (LGL), with K562, an NK-sensitive… 
1986
1986
The functional loss of human natural killer cell activity induced by K562 is reversible via an interleukin-2-dependent mechanism.
1985
1985
Evidence for an early calcium-independent event in the activation of the human natural killer cell cytolytic mechanism.
In this study, we examined the functional status of human natural killer (NK) cells after their direct interaction with the NK… 
1984
1984
Compared mechanisms of tumor cytolysis by human natural killer cells and activated polymorphonuclear leukocytes.
The mechanism(s) of natural killer (NK) cell-mediated cytotoxicity (CMC) remains largely unknown. In this study, we investigated… 
Highly Cited
1981
Highly Cited
1981
T lymphocyte-mediated cytolysis. I. A common mechanism for target recognition in specific and lectin-dependent cytolysis.
In this and the accompanying paper we examine the nature of the interactions between effector cells and target cells leading to… 
1980
1980
The Ultrastructure of the Tubular Complex in the Cytoplasm of Cytolytic T Lymphocytes
The DNA synthesis, the cytolytic activity, and the ultrastructure of cytolytic T lymphocytes (CTL) derived from mixed mouse… 
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