Lamin B1

Known as: LMNB1 
Lamin B1, one of the two B type proteins, is encoded by the human LMNB1 gene. Lamins are components of the nuclear lamina, a fibrous layer on the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
05101519862018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Cellular senescence is a potent tumor-suppressive mechanism that arrests cell proliferation and has been linked to aging. However… (More)
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2012
2012
We report crosstalk between three senescence-inducing conditions, DNA damage response (DDR) defects, oxidative stress (OS) and… (More)
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Highly Cited
2011
Highly Cited
2011
Nuclear lamin B1 (LB1) is a major structural component of the nucleus that appears to be involved in the regulation of many… (More)
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Highly Cited
2011
Highly Cited
2011
Neuronal migration is essential for the development of the mammalian brain. Here, we document severe defects in neuronal… (More)
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Highly Cited
2009
Highly Cited
2009
Duplication of the gene encoding lamin B1 (LMNB1) with increased mRNA and protein levels has been shown to cause severe myelin… (More)
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2009
2009
The dynamic ability of genomes to interact with discrete nuclear compartments appears to be essential for chromatin function… (More)
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Highly Cited
2004
Highly Cited
2004
Lamins are key structural components of the nuclear lamina, an intermediate filament meshwork that lies beneath the inner nuclear… (More)
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Highly Cited
1997
Highly Cited
1997
 A selection of normal human tissues was investigated for the presence of lamins B1, B2, and A-type lamins, using a panel of… (More)
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Highly Cited
1995
Highly Cited
1995
Chromatin condensation and nuclear envelope breakdown are characteristic features of apoptotic cell death, but the mechanisms… (More)
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Highly Cited
1992
Highly Cited
1992
Eukaryotic chromatin is organized into topologically constrained loops that are attached to the nuclear matrix. The regions of… (More)
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