LYN gene

Known as: v-YES-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog Gene, ONCOGENE LYN, V-YES-1 YAMAGUCHI SARCOMA VIRAL RELATED ONCOGENE HOMOLOG 
This gene plays a role in signal transduction.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
051019682017

Papers overview

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2013
2013
HS1 (hematopoietic cell-specific Lyn substrate-1) is a cytoskeletal interactor in the B-cell receptor (BCR) signaling pathway… (More)
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Highly Cited
2010
Highly Cited
2010
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is… (More)
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2010
2010
To understand the molecular mechanisms of metastasis and prognosis of colorectal cancer (CRC), we isolated single cell-derived… (More)
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2009
2009
We targeted LYN, a src-tyosine kinase involved in B-cell activation, in case–control association studies using populations of… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical studies have shown that the tyrosine kinase inhibitor STI571 effectively controls BCR-ABL-positive chronic myelogenous… (More)
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1999
1999
Although nitric oxide (NO) has potent antiplatelet actions, the signaling pathways affected by NO in the platelet are poorly… (More)
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Highly Cited
1995
Highly Cited
1995
Mice homozygous for a disruption at the Lyn locus display abnormalities associated with the B lymphocyte lineage and in mast cell… (More)
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1992
1992
The lymphokine interleukin-3 (IL-3) promotes the growth and survival of immature hematopoietic cells. Previous studies have shown… (More)
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Highly Cited
1991
Highly Cited
1991
Activation of platelets with thrombin and other agonists causes a rapid increase in the phosphorylation of multiple proteins on… (More)
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