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LY96 gene

Known as: MD-2, MD2, MD2 PROTEIN 
National Institutes of Health

Related topics

Related topics

2 relations
LY96 protein, humanLymphocyte Antigen 96

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species…
A literature review concerning the unexpected species differences of the vertebrate innate immune response to lipid IVA was… 
2012
2012
Macrophage genetic reprogramming during chronic peritonitis is augmented by LPS pretreatment.
2009
2009
Mannose binding lectin and lung collectins interact with Toll-like receptor 4 and MD-2 by different mechanisms.
2008
2008
Increased release of sMD-2 during human endotoxemia and sepsis: a role for endothelial cells.
2007
2007
The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist
Lipopolysaccharide (LPS) antagonists inhibit the response of inflammatory cells to LPS, presumably by competitive inhibition, and… 
2005
2005
The Toll-like receptor 4 region Glu24-Pro34 is critical for interaction with MD-2.
2005
2005
MD-2 and Der p 2 — a tale of two cousins or distant relatives?
MD-2, an LPS-binding protein is essential for the recognition of LPS by TLR4. MD-2 belongs to the ML superfamily of lipid-binding… 
2005
2005
The Functional and Structural Properties of MD-2 Required for Lipopolysaccharide Binding Are Absent in MD-11
MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is… 
2004
2004
MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN.
Highly Cited
2001
Highly Cited
2001
N-Linked Glycosylations at Asn26 and Asn114 of Human MD-2 Are Required for Toll-Like Receptor 4-Mediated Activation of NF-κB by Lipopolysaccharide
MD-2 is physically associated with Toll-like receptor 4 (TLR4) and is required for TLR4-mediated LPS signaling. Western blotting… 
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