LY96 gene

Known as: MD-2, MD2, MD2 PROTEIN 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Lipopolysaccharide (LPS), also known as endotoxin, activates the innate immune response through toll-like receptor 4 (TLR4) and… (More)
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Highly Cited
2009
Highly Cited
2009
The lipopolysaccharide (LPS) of Gram negative bacteria is a well-known inducer of the innate immune response. Toll-like receptor… (More)
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Highly Cited
2009
Highly Cited
2009
Aeroallergy results from maladaptive immune responses to ubiquitous, otherwise innocuous environmental proteins. Although the… (More)
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Highly Cited
2007
Highly Cited
2007
Inflammation under sterile conditions is not well understood despite its importance in trauma and autoimmune disease. To… (More)
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Highly Cited
2005
Highly Cited
2005
The mRNA expression levels of 10 toll-like receptors (TLRs) and 21 related genes in total RNA from pooled specimens of fetal… (More)
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Highly Cited
2005
Highly Cited
2005
The detection of Gram-negative LPS depends upon the proper function of the TLR4-MD-2 receptor complex in immune cells. TLR4 is… (More)
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2002
2002
In order to mediate cellular response to lipopolysaccharide (LPS), Toll-like receptor (TLR) 4 must interact with MD-2, a secreted… (More)
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Highly Cited
2001
Highly Cited
2001
The structural features of some proteins of the innate immune system involved in mediating responses to microbial pathogens are… (More)
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Highly Cited
2001
Highly Cited
2001
Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS). MD-2 is associated with TLR4 and imparts LPS responsiveness to… (More)
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Highly Cited
1999
Highly Cited
1999
Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate… (More)
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