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LY379196

Known as: LY 379196 
National Institutes of Health

Papers overview

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2012
2012
Cellular crosstalk between TNF-α, NADPH oxidase, PKCβ2, and C2GNT in human leukocytes.
2005
2005
HIGH GLUCOSE‐INDUCED HUMAN UMBILICAL VEIN ENDOTHELIAL CELL HYPERPERMEABILITY IS DEPENDENT ON PROTEIN KINASE C ACTIVATION AND INDEPENDENT OF THE Ca2+–NITRIC OXIDE SIGNALLING PATHWAY
1. Endothelial barrier dysfunction plays a pivotal role in the pathogenesis of diabetic vascular complications. The precise… 
2004
2004
Protein kinase C-beta inhibition and diabetic microangiopathy: effects on endothelial permeability responses in vitro.
Highly Cited
2004
Highly Cited
2004
Opposing effect of angiopoietin‐1 on VEGF‐mediated disruption of endothelial cell–cell interactions requires activation of PKCβ
Angiopoietin‐1 (Ang1) and vascular endothelial growth factor (VEGF) cooperate in migration and survival of endothelial cells by… 
2004
2004
Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
Protein kinase C betaII (PKCbetaII) promotes colon carcinogenesis. Expression of PKCbetaII in the colon of transgenic mice… 
2003
2003
Protein kinase C beta2-dependent phosphorylation of core 2 GlcNAc-T promotes leukocyte-endothelial cell adhesion: a mechanism underlying capillary occlusion in diabetic retinopathy.
Increased leukocyte-endothelial cell adhesion is a key early event in the development of retinopathy and atherogenesis in… 
2003
2003
Steroids Modulate N-Methyl-D-aspartate-Stimulated [3H]Dopamine Release from Rat Striatum via σ Receptors
Steroids have been proposed as endogenous ligands at σ receptors. In the current study, we examined the ability of steroids to… 
2000
2000
The protein kinase C β–specific inhibitor LY379196 blocks TPA‐induced monocytic differentiation of HL60 cells the protein kinase C β–specific inhibitor LY379196 blocks TPA‐induced monocytic…
The ability of the promyelocytic leukemia HL60 cell line to differentiate in response to various stimuli has provided a widely… 
2000
2000
Protein kinase C beta1 is implicated in the regulation of neuroblastoma cell growth and proliferation.
To investigate a putative involvement of protein kinase C (PKC) isoforms in supporting neuroblastoma cell proliferation, SK-N-BE… 
Highly Cited
1999
Highly Cited
1999
Tyrosine phosphorylation of specific protein kinase C isoenzymes participates in insulin stimulation of glucose transport in primary cultures of rat skeletal muscle.
Several reports indicate that protein kinase C (PKC) plays a role in insulin-induced glucose transport in certain cells. The… 
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