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LY 315920

Known as: LY-315920, LY315920, LY333013 
 
National Institutes of Health

Papers overview

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2018
2018
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long… Expand
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2018
2018
There is a clear, unmet need for effective, lightweight, shelf-stable and economical snakebite envenoming therapies that can be… Expand
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Highly Cited
2016
Highly Cited
2016
Snakebite remains a neglected medical problem of the developing world with up to 125,000 deaths each year despite more than a… Expand
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Highly Cited
2008
Highly Cited
2008
We report a series of inhibitors of secreted phospholipases A2 (sPLA2s) based on substituted indoles, 6,7-benzoindoles, and… Expand
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Highly Cited
2007
Highly Cited
2007
An efficient and regioselective synthesis of 4- and 7-alkoxyindoles has been developed from commercially available starting… Expand
Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the efficacy and safety of a selective inhibitor of secretory phospholipase (sPLA2), LY333013, in the… Expand
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2005
2005
PURPOSE How vitamin A contributes to the maintenance of the wet-surfaced phenotype at the ocular surface is not well understood… Expand
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2005
2005
The possible roles of secretory phospholipases A2 (sPLA2) in asthma include the release of arachidonic acid from cellular… Expand
Highly Cited
1999
Highly Cited
1999
LY315920 is a potent, selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic… Expand
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Highly Cited
1996
Highly Cited
1996
The preceding papers of this series detail the development of functionalized indole-3-acetamides as inhibitors of hnps-PLA2. We… Expand