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LY 315920

Known as: LY-315920, LY315920, LY333013 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long… 
2018
2018
There is a clear, unmet need for effective, lightweight, shelf-stable and economical snakebite envenoming therapies that can be… 
Highly Cited
2016
Highly Cited
2016
Snakebite remains a neglected medical problem of the developing world with up to 125,000 deaths each year despite more than a… 
2014
2014
Lung cancer is the leading cause of cancer death worldwide. There is an urgent need for early diagnostic tools and novel… 
Highly Cited
2008
Highly Cited
2008
We report a series of inhibitors of secreted phospholipases A2 (sPLA2s) based on substituted indoles, 6,7-benzoindoles, and… 
Highly Cited
2007
Highly Cited
2007
An efficient and regioselective synthesis of 4- and 7-alkoxyindoles has been developed from commercially available starting… 
Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the efficacy and safety of a selective inhibitor of secretory phospholipase (sPLA2), LY333013, in the… 
2005
2005
PURPOSE How vitamin A contributes to the maintenance of the wet-surfaced phenotype at the ocular surface is not well understood… 
Highly Cited
1999
Highly Cited
1999
LY315920 is a potent, selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic… 
Highly Cited
1996
Highly Cited
1996
The preceding papers of this series detail the development of functionalized indole-3-acetamides as inhibitors of hnps-PLA2. We…