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varespladib methyl

 
National Institutes of Health

Papers overview

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2019
2019
Lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) is an enzyme family of phospholipase A 2 produced by the inflammatory cell… Expand
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Review
2013
Review
2013
Introduction: Cardiovascular disease is the most common cause of morbidity and mortality worldwide. Inflammation is responsible… Expand
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Review
2012
Review
2012
Certain members of the phospholipase A(2) superfamily of enzymes have established causal involvement in atherosclerosis, thus at… Expand
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2011
2011
AIMS To investigate the effects of secretory phospholipase A2 (sPLA(2)) inhibition on plasma lipoproteins. Secretory… Expand
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2011
2011
BackgroundThe action of secretory phospholipase A2 (sPLA2) on lipoproteins may render them more susceptible to oxidation, thereby… Expand
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2011
2011
PurposeSecretory phospholipase A2 group IIA (sPLA2−IIA) concentration and activity are associated with increased risk of… Expand
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2011
2011
Secretory phospholipase A(2) (sPLA(2)) represents a family of isoenzymes that participate in lipoprotein and inflammatory… Expand
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2010
2010
OBJECTIVES The purpose of this study was to investigate the effects of varespladib on cardiovascular biomarkers in acute coronary… Expand
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2010
Review
2010
IMPORTANCE OF THE FIELD The high risk of recurrent cardiovascular events amongst patients with cardiovascular disease receiving… Expand
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2009
2009
Varespladib methyl is an oral secretory phospholipase A2 inhibitor that is being developed by Anthera Pharmaceuticals Inc for the… Expand
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