LY 303366

Known as: LY-303366, LY303366 
 
National Institutes of Health

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Broader (1)

anidulafungin

Papers overview

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2003
2003
Antifungal activity of the echinocandin anidulafungin (VER002, LY-303366) against yeast pathogens: a comparative study with M27-A microdilution method.
This study further evaluated the in vitro activity of anidulafungin (VER002, Versicor Inc.) (LY303366) against 460 clinical yeast… Expand
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Highly Cited
2001
Highly Cited
2001
Pharmacokinetic and pharmacodynamic modeling of anidulafungin (LY303366): reappraisal of its efficacy in neutropenic animal models of opportunistic mycoses using optimal plasma sampling.
The compartmental pharmacokinetics of anidulafungin (VER-002; formerly LY303366) in plasma were characterized with normal rabbits… Expand
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Highly Cited
2000
Highly Cited
2000
Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans.
The postantifungal effect (PAFE) of fluconazole, MK-0991, LY303366, and amphotericin B was determined against isolates of Candida… Expand
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1999
1999
Antifungal activity of LY303366, a novel echinocandin B, in experimental disseminated candidiasis in rabbits.
The safety and antifungal activity of LY303366 (LY), a new broad-spectrum semisynthetic echinocandin, were studied against… Expand
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Highly Cited
1998
Highly Cited
1998
Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts.
The in vitro antifungal activities of SCH56592, MK-0991, and LY303366 against 83 isolates of Acremonium strictum, Aspergillus… Expand
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Highly Cited
1998
Highly Cited
1998
Influence of test conditions on antifungal time-kill curve results: proposal for standardized methods.
This study was designed to examine the effects of antifungal carryover, agitation, and starting inoculum on the results of time… Expand
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1998
1998
Activity of MK-0991 (L-743,872), a new echinocandin, compared with those of LY303366 and four other antifungal agents tested against blood stream isolates of Candida spp.
MK-0991 (formerly L-743,872) is a water soluble semisynthetic echinocandin that possess potent, broad-spectrum antifungal… Expand
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1997
1997
In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species.
The in vitro activities of LY-303366, a new semisynthetic echinocandin, and comparators amphotericin B, 5-fluorocytosine… Expand
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1997
1997
In vitro susceptibilities of clinical yeast isolates to a new echinocandin derivative, LY303366, and other antifungal agents.
LY303366 is a new semisynthetic echinocandin derivative with potent, broad-spectrum fungicidal activity. We investigated the in… Expand
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Review
1994
Review
1994
Antibiotics that inhibit fungal cell wall development.
The discovery of antifungal agents that possess selective toxicity against the eukaryotic fungal cell remains an important… Expand
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