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LY 290042

Known as: LY-290042, LY290042 
National Institutes of Health

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2 relations

Broader (2)

ChromonesMorpholines

Papers overview

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2011
2011
Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells.
One of the hurdles of cord blood (CB) transplantation is delayed hematopoietic engraftment. Previously, we demonstrated that… 
Highly Cited
2010
Highly Cited
2010
Growth differentiation factor 15 acts anti‐apoptotic and pro‐hypertrophic in adult cardiomyocytes
Growth differentiation factor 15 (GDF15) is induced during heart failure development, and may influence different processes in… 
Highly Cited
2010
Highly Cited
2010
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium.
2010
2010
Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells.
Highly Cited
2009
Highly Cited
2009
NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells*
Skeletal muscle is one of the main physiological targets of insulin, a hormone that triggers a complex signaling cascade and that… 
Highly Cited
2008
Highly Cited
2008
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway.
The ligand hepatocyte growth factor/scatter factor (HGF) and its receptor tyrosine kinase, c-Met, are highly expressed in most… 
Highly Cited
2004
Highly Cited
2004
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.
2002
2002
Apigenin and LY294002 prolong EGF‐stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation
Highly Cited
2002
Highly Cited
2002
Requirement of Phosphatidylinositol 3-Kinase Activation and Calcium Influx for Leukotriene B4-induced Enzyme Release*
Leukotriene B4(LTB4) is a potent lipid mediator involved in host defense and inflammatory responses. It causes chemotaxis… 
Highly Cited
1998
Highly Cited
1998
Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on…
Phosphatidylinositol 3-kinase (PI 3-kinase) and protein kinase B are critical players in cell proliferation and survival. Their… 
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