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LY 290042

Known as: LY-290042, LY290042 
 
National Institutes of Health

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Related topics

2 relations

Broader (2)

ChromonesMorpholines

Papers overview

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2011
2011
Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells.
One of the hurdles of cord blood (CB) transplantation is delayed hematopoietic engraftment. Previously, we demonstrated that… Expand
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Highly Cited
2010
Highly Cited
2010
Growth differentiation factor 15 acts anti‐apoptotic and pro‐hypertrophic in adult cardiomyocytes
Growth differentiation factor 15 (GDF15) is induced during heart failure development, and may influence different processes in… Expand
Highly Cited
2010
Highly Cited
2010
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium.
Although nonsteroidal anti-inflammatory drugs (NSAIDs) provide important control of pain and inflammation, they have been… Expand
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Highly Cited
2009
Highly Cited
2009
NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells*
Skeletal muscle is one of the main physiological targets of insulin, a hormone that triggers a complex signaling cascade and that… Expand
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Highly Cited
2008
Highly Cited
2008
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway.
The ligand hepatocyte growth factor/scatter factor (HGF) and its receptor tyrosine kinase, c-Met, are highly expressed in most… Expand
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Highly Cited
2004
Highly Cited
2004
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.
Polybrominated diphenyl ethers (PBDEs) are an important class of flame retardants. Because of their presence in maternal milk and… Expand
2004
2004
Decay-accelerating factor induction on vascular endothelium by vascular endothelial growth factor (VEGF) is mediated via a VEGF receptor-2 (VEGF-R2)- and protein kinase C-alpha/epsilon (PKCalpha…
Decay-accelerating factor (DAF), a membrane-bound complement regulatory protein, is up-regulated on endothelial cells (ECs… Expand
Highly Cited
2002
Highly Cited
2002
Requirement of Phosphatidylinositol 3-Kinase Activation and Calcium Influx for Leukotriene B4-induced Enzyme Release*
Leukotriene B4(LTB4) is a potent lipid mediator involved in host defense and inflammatory responses. It causes chemotaxis… Expand
2002
2002
Apigenin and LY294002 prolong EGF‐stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation
In rat pheochromocytoma cell line (PC12) cells, initial epidermal growth factor (EGF)‐stimulated extracellular signal‐regulated… Expand
Highly Cited
1998
Highly Cited
1998
Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on…
Phosphatidylinositol 3-kinase (PI 3-kinase) and protein kinase B are critical players in cell proliferation and survival. Their… Expand
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