LY 288513

This study investigated the behavioral mechanisms underlying the anxiogenic, or anxiolytic mediated effects of CCK(2) receptor… Expand

Defensive rage behavior is mediated over a descending pathway from the medial hypothalamus to the dorsolateral midbrain… Expand

SummaryCholecystokinin (CCK) is one of the most abundant neuropeptides in the brain. It is found in the highest levels in… Expand

Pre-pulse inhibition (PPI) of the acoustic startle response is the diminution of the startle response when the startle stimulus… Expand

The activity of LY288513, an investigational cholecystokinin (CCK)B antagonist, was evaluated in a wide range of pharmacological… Expand

The potency and specificity of five proposed cholecystokinin-B receptor antagonists, YM022, RP73870, L-740,093, L-365,260 and… Expand

IN order to explore the potential clinical utility of CCK-B antagonists for the treatment of nicotine withdrawal symptoms, the… Expand

In order to investigate the involvement of cholecystokinin (CCK) in the regulation of anxiety, the effect of the selective non… Expand

The diphenylpyrazolidinone cholecystokinin (CCK)-B antagonist LY262691 has recently been demonstrated to decrease the number of… Expand

In order to explore the potential clinical utility of CCK-B antagonists for the treatment of benzodiazepine withdrawal symptoms… Expand