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LY 2121260
Known as:
LY-2121260
, LY2121260
National Institutes of Health
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Papers overview
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2015
2015
Lack of glibenclamide response in a case of permanent neonatal diabetes caused by incomplete inactivation of glucokinase.
J. Oriola
,
F. Moreno
,
+4 authors
M. Navas
JIMD Reports
2015
Corpus ID: 24323148
BACKGROUND Hypoglycaemic drugs that close the KATP channel have been tested in patients with permanent neonatal diabetes due to…
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Review
2014
Review
2014
Recent updates on glucokinase activators for the treatment of type 2 diabetes mellitus.
A. S. Grewal
,
B. S. Sekhon
,
V. Lather
Mini-Reviews in Medical Chemistry
2014
Corpus ID: 24408441
Glucose-phosphorylating enzyme, glucokinase (GK) plays a major role in glucose homeostasis primarily through its regulatory…
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2012
2012
Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260.
S. Baltrusch
,
H. Schmitt
,
A. Brix
,
Sara Langer
,
S. Lenzen
Biochemical Pharmacology
2012
Corpus ID: 11216204
2009
2009
Effects of glucokinase activators GKA50 and LY2121260 on proliferation and apoptosis in pancreatic INS-1 beta cells
P. Wei
,
M. Shi
,
S. Barnum
,
H. Cho
,
T. Carlson
,
J. D. Fraser
Diabetologia
2009
Corpus ID: 21358728
Aims/hypothesisGlucokinase (GK), an enzyme that phosphorylates glucose to form glucose 6-phosphate, serves as the glucose sensor…
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Highly Cited
2005
Highly Cited
2005
A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
A. Efanov
,
David G. Barrett
,
+12 authors
J. Gromada
Endocrinology
2005
Corpus ID: 42862796
The glucose-sensing enzyme glucokinase (GK) plays a key role in glucose metabolism. We report here the effects of a novel…
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