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National Institutes of Health
Semantic Scholar uses AI to extract papers important to this topic.
Lack of glibenclamide response in a case of permanent neonatal diabetes caused by incomplete inactivation of glucokinase.
Corpus ID: 24323148
BACKGROUND Hypoglycaemic drugs that close the KATP channel have been tested in patients with permanent neonatal diabetes due to…
Recent updates on glucokinase activators for the treatment of type 2 diabetes mellitus.
A. S. Grewal
B. S. Sekhon
Mini reviews in medicinal chemistry
Corpus ID: 24408441
Glucose-phosphorylating enzyme, glucokinase (GK) plays a major role in glucose homeostasis primarily through its regulatory…
Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260.
Corpus ID: 11216204
Effects of glucokinase activators GKA50 and LY2121260 on proliferation and apoptosis in pancreatic INS-1 beta cells
J. D. Fraser
Corpus ID: 21358728
Aims/hypothesisGlucokinase (GK), an enzyme that phosphorylates glucose to form glucose 6-phosphate, serves as the glucose sensor…
A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
David G Barrett
Corpus ID: 42862796
The glucose-sensing enzyme glucokinase (GK) plays a key role in glucose metabolism. We report here the effects of a novel…
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