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LSP1 gene

Known as: Lymphocyte-Specific Protein 1 Gene, 52 kDa Phosphoprotein, LYMPHOCYTE-SPECIFIC PROTEIN 
Lymphocyte-specific protein 1 (339 aa, ~37 kDa) is encoded by the human LSP1 gene. This protein binds actin and may play a role in neutrophil… 
National Institutes of Health

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Related topics

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ChemotaxisSignal TransductionSignaling Pathway Gene

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LSP1 wt Allele

Papers overview

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2012
2012
Different microvascular permeability responses elicited by the CXC chemokines MIP-2 and KC during leukocyte recruitment: role of LSP1.
2010
2010
Risk of genome-wide association study newly identified genetic variants for breast cancer in Chinese women of Heilongjiang Province
Recent genome-wide association studies have identified seven single nucleotide polymorphisms (SNPs) associated with breast cancer… 
Highly Cited
2007
Highly Cited
2007
Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells
Dendritic cells (DCs) capture and internalize human immunodeficiency virus (HIV)-1 through C-type lectins, including DC-SIGN… 
Highly Cited
2002
Highly Cited
2002
Modulation of Mac-1 (CD11b/CD18)-Mediated Adhesion by the Leukocyte-Specific Protein 1 Is Key to Its Role in Neutrophil Polarization and Chemotaxis1
Leukocyte-specific protein 1 (LSP1) is an intracellular filamentous-actin binding protein which modulates cell motility. The… 
Highly Cited
2001
Highly Cited
2001
Leukocyte‐specific gene 1 protein (LSP1) is involved in chemokine KC‐activated cytoskeletal reorganization in murine neutrophils in vitro
Leukocyte‐specific gene 1 protein (LSP1) is a cytoskeletal‐associated protein of leukocytes that in vitro cross‐links F‐actin… 
Highly Cited
2000
Highly Cited
2000
LSP1 modulates leukocyte populations in resting and inflamed peritoneum.
Lymphocyte-specific protein 1, recently renamed leukocyte-specific protein 1 (LSP1), is an F-actin binding protein expressed in… 
1996
1996
Characterization and purification of a protein kinase C substrate in human B cells. Identification as lymphocyte-specific protein 1 (LSP1).
Incubation of B-chronic lymphocytic leukemia (B-CLL) cells with phorbol esters resulted in the phosphorylation of two major PKC… 
Highly Cited
1994
Highly Cited
1994
Identification of a protein kinase associated with the cytoplasmic domain of the p60 tumor necrosis factor receptor.
Tumor necrosis factor (TNF) has been shown to bind two distinct receptors, designated p60 and p80, with high affinity, resulting… 
Highly Cited
1994
Highly Cited
1994
The 47-kD protein increased in neutrophil actin dysfunction with 47- and 89-kD protein abnormalities is lymphocyte-specific protein.
A male child born of related parents suffered recurrent infections because of neutrophil actin dysfunction with increased amounts… 
1990
1990
Molecular cloning and characterization of WP34, a phosphorylated human lymphocyte differentiation and activation antigen
An absorbed antiserum was made by incubating a cytotoxic T lymphocyte immune antiserum with the T cell leukemia HPB‐ALL, thus… 
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