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LRRC8A gene

Known as: FLJ10337, LRRC8A, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 8A 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Flow fluorometry quantification of anion channel VRAC subunit LRRC8A at the membrane of living U937 cells
ABSTRACT Assessing the expression of channels on the cell membrane is a necessary step in studying the functioning of ion… 
2020
2020
Deficient of LRRC8A attenuates hypoxia-induced necrosis in 3T3-L1 cells
ABSTRACT Under acute hypoxia, multiple ion channels on the cell membrane are activated, causing cell swelling and eventually… 
2019
2019
Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells.
Although peritoneal lavage with distilled water performed after surgery prevents peritoneal seeding, cancer cells may avoid… 
2019
2019
Tweety Homologs (TTYH) Freshly Join the Journey of Molecular Identification of the VRAC/VSOR Channel Pore
and functions of animal cells under physiological and pathological conditions. Two types of chloride channels are directly… 
2018
2018
LRRC 8 / VRAC anion channels enhance β-cell glucose sensing and insulin secretion
Glucose homeostasis depends critically on insulin that is secreted by pancreatic β-cells. Serum glucose, which is directly sensed… 
2017
2017
Cisplatin activates volume sensitive LRRC8 channel mediated currents in Xenopus oocytes
ABSTRACT LRRC8 proteins have been shown to underlie the ubiquitous volume regulated anion channel (VRAC). VRAC channels are… 
2017
2017
Erratum: Microtubule minus-end regulation at spindle poles by an ASPM–katanin complex
This corrects the article DOI: 10.1038/ncb3511 
2017
2017
Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Nature Cell Biology http://dx.doi.org/10.1038/ncb3514 (2017); published online 24 April 2017; corrected after print 25 April 2017… 
Review
2016
Review
2016
Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR)
The volume-regulated anion channel (VRAC), also known as the volume-sensitive outwardly rectifying (VSOR) anion channel or the… 
2014
2014
Of volume regulation, arterial constriction, and apoptotic breakdown
This month’s installment of Generally Physiological concerns the identification of a membrane protein that plays a crucial role… 
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