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LRIG1 gene

Known as: LEUCINE-RICH REPEATS- AND IMMUNOGLOBULIN-LIKE DOMAINS-CONTAINING PROTEIN 1, LIG1, LRIG1 
This gene is involved in the regulation of signal transduction.
National Institutes of Health

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Broader (1)

LIG1 gene
LRIG1 wt AlleleLeucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1Signal Transductionprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MicroRNA-590-3p enhances the radioresistance in glioblastoma cells by targeting LRIG1.
microRNA (miR)-590 has been found to serve potential roles in cancer development; however, the expression and function of miR-590… 
2015
2015
Abstract 662: USP8 modulates ubiquitination of LRIG1 for Met degradation
The Met receptor tyrosine kinase is an attractive target for cancer therapy as it promotes invasive tumor growth. SAIT301 is a… 
2015
2015
Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder cancer cells to cisplatin.
Cisplatin (cis-diaminodichloroplatinum, CDDP) is one of the most effective chemotherapeutic agents that has been widely used in… 
2014
2014
Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine.
2012
2012
LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling.
Smac mimetics block inhibitor of apoptosis proteins to trigger TNFα-dependent apoptosis in cancer cells. However, only a small… 
2010
2010
LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix
Abstract Background. The human leucine-rich repeats and immunoglobulin-like domains (LRIG) protein family comprises LRIG1, 2, and… 
Highly Cited
2009
Highly Cited
2009
Current smoking‐specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer
Cigarette smoking is the main risk factor for the development of squamous cell lung carcinoma (SCC). However, the smoking‐related… 
2009
2009
Pitfalls in immunohistochemical validation of tumor marker expression--exemplified in invasive cancer of the uterine cervix.
Highly Cited
2006
Highly Cited
2006
Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors
We have previously characterized three human leucine-rich repeats and immunoglobulin-like domains (LRIG) genes and proteins… 
Highly Cited
1996
Highly Cited
1996
cDNA Cloning of a Novel Membrane Glycoprotein That Is Expressed Specifically in Glial Cells in the Mouse Brain
A cDNA encoding a protein designated as LIG-1 has been cloned and characterized. A fragment of this cDNA was found previously in… 
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