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LRIG1 wt Allele

Known as: Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 wt Allele, Leucine-Rich Repeat Protein LRIG1 Gene, LIG-1 
Human LRIG1 wild-type allele is located in the vicinity of 3p14 and is approximately 122 kb in length. This allele, which encodes leucine-rich… Expand
National Institutes of Health

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4 relations
LRIG1 geneLeucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1Signal Transductionprotein protein interaction

Papers overview

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2016
2016
Identification of novel selective MMP-9 inhibitors as potential anti-metastatic lead using structure-based hierarchical virtual screening and molecular dynamics simulation.
MMP-9 is an attractive target for the development of new anticancer drugs. In the current study, pharmacophore modeling was… Expand
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2014
2014
Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
Background:The incidence of human papillomavirus (HPV)-associated oropharyngeal cancer has increased rapidly during the past… Expand
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2012
2012
The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision repair outcome at CAG/CTG repeats.
Expansion of CAG/CTG repeats is the underlying cause of >14 genetic disorders, including Huntington's disease (HD) and myotonic… Expand
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2011
2011
CHARACTERIZATION OF ALKALINE LIGNINS FOR USE IN PHENOL-FORMALDEHYDE AND EPOXY RESINS
Besides polyurethanes and polyesters, phenolic and epoxy resins are the most prominent applications for technical lignins in… Expand
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2011
2011
Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1.
Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a recently discovered negative regulator of growth factor… Expand
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Highly Cited
2004
Highly Cited
2004
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases.
The molecular mechanisms by which mammalian receptor tyrosine kinases are negatively regulated remain largely unexplored… Expand
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2004
2004
Topical Liposomal Gel of Idoxuridine for the Treatment of Herpes Simplex: Pharmaceutical and Clinical Implications
The optimization of the method of preparation of idoxuridine (IDU) liposomes by the reverse phase evaporation (REV) method was… Expand
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Highly Cited
2002
Highly Cited
2002
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia.
The gene encoding a transmembrane glycoprotein LIG-1, of which the extracellular region was organized with the leucine-rich… Expand
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