Semantic Scholar uses AI to extract papers important to this topic.
Hsp104 is a hexameric AAA+ ATPase and protein disaggregase found in yeast, which couples ATP hydrolysis to the dissolution of… Expand Significance The 26S proteasome is a large multisubunit complex that executes the degradation of intracellular proteins marked… Expand The Type VI secretion system (T6SS) is a versatile machine that delivers toxins into either eukaryotic or bacterial cells. It… Expand BackgroundLrrk2, a gene linked to Parkinson’s disease, encodes a large scaffolding protein with kinase and GTPase activities… Expand The hexameric AAA+ (ATPase associated with various cellular activities) chaperone ClpB reactivates protein aggregates in… Expand Summary Eukaryotic TIP49a (Pontin) and TIP49b (Reptin) AAA+ ATPases play essential roles in key cellular processes. How their… Expand The TIP49a and TIP49b proteins belong to the family of AAA+ ATPases and play essential roles in vital processes such as… Expand Molecular machines belonging to the AAA+ superfamily of ATPases use NTP hydrolysis to remodel their versatile substrates. The… Expand Clamp-loader complexes are heteropentameric AAA+ ATPases that load sliding clamps onto DNA. The structure of the nucleotide-free… Expand The AAA(+) ATPase component of magnesium chelatase (ChlI) drives the insertion of Mg(2+) into protoporphyrin IX; this is the… Expand