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LONP1 protein, human

Known as: Lon peptidase 1, human, mitochondrial AAA+ Lon protease, human 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

ATP-Dependent ProteasesMitochondrial Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase.
Hsp104 is a hexameric AAA+ ATPase and protein disaggregase found in yeast, which couples ATP hydrolysis to the dissolution of… Expand
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Highly Cited
2017
Highly Cited
2017
Structural insights into the functional cycle of the ATPase module of the 26S proteasome
Significance The 26S proteasome is a large multisubunit complex that executes the degradation of intracellular proteins marked… Expand
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2016
2016
Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli
The Type VI secretion system (T6SS) is a versatile machine that delivers toxins into either eukaryotic or bacterial cells. It… Expand
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Highly Cited
2015
Highly Cited
2015
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate
BackgroundLrrk2, a gene linked to Parkinson’s disease, encodes a large scaffolding protein with kinase and GTPase activities… Expand
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2015
2015
ClpB dynamics is driven by its ATPase cycle and regulated by the DnaK system and substrate proteins.
The hexameric AAA+ (ATPase associated with various cellular activities) chaperone ClpB reactivates protein aggregates in… Expand
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2014
2014
Lytic Water Dynamics Reveal Evolutionarily Conserved Mechanisms of ATP Hydrolysis by TIP49 AAA+ ATPases
Summary Eukaryotic TIP49a (Pontin) and TIP49b (Reptin) AAA+ ATPases play essential roles in key cellular processes. How their… Expand
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2012
2012
Large-scale conformational flexibility determines the properties of AAA+ TIP49 ATPases.
The TIP49a and TIP49b proteins belong to the family of AAA+ ATPases and play essential roles in vital processes such as… Expand
2009
2009
Functional roles of the pre-sensor I insertion sequence in an AAA+ bacterial enhancer binding protein
Molecular machines belonging to the AAA+ superfamily of ATPases use NTP hydrolysis to remodel their versatile substrates. The… Expand
Highly Cited
2004
Highly Cited
2004
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex.
Clamp-loader complexes are heteropentameric AAA+ ATPases that load sliding clamps onto DNA. The structure of the nucleotide-free… Expand
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Highly Cited
2003
Highly Cited
2003
The ATPase activity of the ChlI subunit of magnesium chelatase and formation of a heptameric AAA+ ring.
The AAA(+) ATPase component of magnesium chelatase (ChlI) drives the insertion of Mg(2+) into protoporphyrin IX; this is the… Expand
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