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LIPC gene

Known as: HEPATIC LIPASE, HL, Triacylglycerol lipase 
This gene is involved in lipid metabolism.
National Institutes of Health

Related topics

Related topics

6 relations
HydrolysisHyperlipidemiaLIPC protein, humanLipase

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LIPC wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Liver fat and insulin resistance are independently associated with the -514C>T polymorphism of the hepatic lipase gene.
CONTEXT Liver fat predicts insulin resistance in humans. So far, there is not much information on genetic determinants of liver… 
Highly Cited
1999
Highly Cited
1999
Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations.
Hepatic lipase is an important determinant of plasma HDL concentration and LDL subclass distribution and may therefore influence… 
Highly Cited
1991
Highly Cited
1991
A dose-response relationship between sex hormone-induced change in hepatic triglyceride lipase and high-density lipoprotein cholesterol in postmenopausal women.
Highly Cited
1987
Highly Cited
1987
Cloning of rat hepatic lipase cDNA: evidence for a lipase gene family.
Clones for rat hepatic lipase were isolated by probing a rat liver cDNA library in lambda gt11 with an oligonucleotide… 
Highly Cited
1987
Highly Cited
1987
Human hepatic triglyceride lipase: cDNA cloning, amino acid sequence and expression in a cultured cell line.
By immunoscreening of a human cDNA expression library and hybridization of colonies, four partially overlapping cDNA clones of… 
Highly Cited
1982
Highly Cited
1982
Roles of Lipoprotein Lipase and Hepatic Triglyceride Lipase in the Catabolism In Vivo of Triglyceride‐Rich Lipoproteins
To define the roles, In vivo, of hepatic triglyceride lipase and lipoprotein lipase in the catabolism of trlglyceiide-rlch… 
Highly Cited
1980
Highly Cited
1980
A selective decline of postheparin plasma hepatic triglyceride lipase in hypothyroid rats.
Highly Cited
1979
Highly Cited
1979
Postheparin plasma triglyceride lipases in chronic hemodialysis: evidence for a role for hepatic lipase in lipoprotein metabolism.
1977
1977
The Effects of Fasting and Streptozotocin Diabetes on Hepatic Triglyceride Lipase Activity in the Rat
The activity of hepatic triglyceride lipase in the rat was reduced by fasting. Withdrawal of insulin from insulin-treated… 
Highly Cited
1970
Highly Cited
1970
Studies on African Pygmies. IV. A comparative study of the HL-A polymorphism in the Babinga Pygmies and other African and Caucasian populations.
Population studies of complex polymorphisms such as the Rhesus and Gm system have contributed substantially to an understanding… 
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