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LHX2 gene

Known as: LIM Homeobox 2 Gene, LIM HOX GENE 2, LIM homeobox 2 
This gene plays a role in transcriptional regulation and has been implicated in the control of differentiation. The gene is also postulated to be… 
National Institutes of Health

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9 relations
Cell Differentiation processHomo sapiensLHX2 protein, humanLHX2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
miR‐144 reverses cisplatin resistance in cervical cancer via targeting LHX2
Mounting evidence showed that microRNAs involve in development and chemoresistance of various human cancers. We explored the… 
2019
2019
LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells
Human induced pluripotent stem (iPS) cells can differentiate into hepatocyte lineages, although the phenotype of the… 
2016
2016
Genes expressed in mouse cortical progenitors are enriched in Pax, Lhx, and Sox transcription factor putative binding sites
Highly Cited
2014
Highly Cited
2014
LIM‐homeobox gene 2 promotes tumor growth and metastasis by inducing autocrine and paracrine PDGF‐B signaling
2014
2014
Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclasts
The LIM homeobox 2 (Lhx2) transcription factor Lhx2 has a variety of functions, including neural induction, morphogenesis, and… 
Highly Cited
2012
Highly Cited
2012
Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina
Purpose To examine the potential of NIH-maintained human embryonic stem cell (hESC) lines TE03 and UC06 to differentiate into… 
Highly Cited
2011
Highly Cited
2011
In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2.
Identification of genes involved in in vitro differentiation induction of embryonic stem cells (ESCs) into hematopoietic stem… 
2010
2010
Mutations in the LHX2 gene are not a frequent cause of micro/anophthalmia
Purpose Microphthalmia and anophthalmia are at the severe end of the spectrum of abnormalities in ocular development. A few genes… 
Highly Cited
2002
Highly Cited
2002
Hematopoietic progenitor/stem cells immortalized by Lhx2 generate functional hematopoietic cells in vivo.
Hematopoietic stem cells (HSCs) are unique in their capacity to maintain blood formation following transplantation into… 
Highly Cited
1999
Highly Cited
1999
Conservation of the expression and function of apterous orthologs in Drosophila and mammals.
The Drosophila apterous (ap) gene encodes a protein of the LIM-homeodomain family. Many transcription factors of this class have… 
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