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LCZ 696

Known as: LCZ-696, LCZ696 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Backgound: Current drug therapy for the management of arterial hypertension and heart failure has provided substantial benefits… 
2017
2017
Background To determine the effectiveness and safety of LCZ696 for the clinical treatment of hypertension, we performed a meta… 
2017
2017
Despite significant therapeutic advances, patients with chronic heart failure and reduced ejection fraction (HFrEF) remain at… 
Review
2016
Review
2016
Heart failure is a global problem with elevated prevalence, and it is associated with substantial cardiovascular morbidity and… 
2016
2016
The treatment of heart failure with reduced ejection fraction (HFREF) is a fascinating story of our evolving understanding of how… 
2015
2015
Angiotensin-converting enzyme (ACE) inhibitors are the cornerstone of the treatment for heart failure and a reduced ejection… 
Review
2013
Review
2013
There is a persistent need for the development of new antihypertensive drugs, because the control of blood pressure is still not… 
2013
2013
Objective: LCZ696 is a first-in-class angiotensin receptor neprilysin inhibitor (ARNI) being developed for the treatment of… 
2010
2010
Introduction: In the setting of heart failure (HF), chronic RAAS activation is detrimental, while NEP (neprilysin, NEP 24.11…