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LCE3C gene

Known as: LCE3C, LATE ENVELOPE PROTEIN 15, LEP15 
National Institutes of Health

Related topics

Related topics

1 relation
LCE1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan divergence
BackgroundA common, 32kb deletion of LCE3B and LCE3C genes is strongly associated with psoriasis. We recently found that this… 
2016
2016
Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia
Deletion of the late cornified envelope (LCE) proteins LCE3B and LCE3C is a strong and widely replicated psoriasis risk factor… 
Review
2015
Review
2015
Association of the late cornified envelope-3 genes with psoriasis and psoriatic arthritis: a systematic review.
Review
2014
Review
2014
Genetics of psoriatic arthritis.
Highly Cited
2011
Highly Cited
2011
Psoriasis risk genes of the late cornified envelope-3 group are distinctly expressed compared with genes of other LCE groups.
2011
2011
Deletion of the late cornified envelope genes LCE3C and LCE3B is associated with psoriasis in a Chinese population.
A common deletion comprising LCE3B and LCE3C, members of the late cornified envelope (LCE) gene cluster, has been shown to be… 
2011
2011
Deletion of LCE3C and LCE3B is a susceptibility factor for psoriatic arthritis: a study in Spanish and Italian populations and meta-analysis.
OBJECTIVE The LCE3C_LCE3B-del variant is associated with psoriasis and rheumatoid arthritis. Its role in psoriatic arthritis (PsA… 
Highly Cited
2011
Highly Cited
2011
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.
A multicenter meta-analysis including data from 9,389 psoriasis patients and 9,477 control subjects was performed to investigate… 
2011
2011
Deletion of the late cornified envelope genes LCE3B and LCE3C may promote chronic hand eczema with allergic contact dermatitis.
BACKGROUND Genetically determined defects in epidermal skin barrier function may contribute to the development of irritant and/or… 
Highly Cited
2009
Highly Cited
2009
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis
Psoriasis is a common inflammatory skin disease with a prevalence of 2–3% in individuals of European ancestry. In a genome-wide… 
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