LAG3 wt Allele

Known as: FDC, CD223, LAG-3 
Human LAG3 wild-type allele is located in the vicinity of 12p13.32 and is approximately 6 kb in length. This allele, which encodes lymphocyte… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0102019902018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Adoptive transfer of tumor-infiltrating lymphocytes (TILs) can mediate regression of metastatic melanoma; however, TILs are a… (More)
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Highly Cited
2013
Highly Cited
2013
CD4+ type 1 T regulatory (Tr1) cells are induced in the periphery and have a pivotal role in promoting and maintaining tolerance… (More)
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Highly Cited
2012
Highly Cited
2012
Inhibitory receptors on immune cells are pivotal regulators of immune escape in cancer. Among these inhibitory receptors, CTLA-4… (More)
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Highly Cited
2010
Highly Cited
2010
NY-ESO-1 is a "cancer-testis" antigen frequently expressed in epithelial ovarian cancer (EOC) and is among the most immunogenic… (More)
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Highly Cited
2008
Highly Cited
2008
Lymphocyte activation gene-3 (LAG-3) is a CD4-related transmembrane protein expressed by regulatory T cells that binds MHC II on… (More)
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Highly Cited
2007
Highly Cited
2007
Lymphocyte activation gene-3 (LAG-3) is a cell-surface molecule with diverse biologic effects on T cell function. We recently… (More)
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Highly Cited
2004
Highly Cited
2004
Regulatory T cells (Tregs) limit autoimmunity but also attenuate the magnitude of antipathogen and antitumor immunity… (More)
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Highly Cited
2004
Highly Cited
2004
Lymphocyte activation gene-3 (LAG-3) is a CD4-related, activation-induced cell surface molecule that binds to MHC class II with… (More)
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Highly Cited
2000
Highly Cited
2000
Notch signalling controls growth, differentiation and patterning during normal animal development; in humans, aberrant Notch… (More)
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Highly Cited
1990
Highly Cited
1990
We have identified a novel human gene of the Ig superfamily, designated LAG-3. Expression of this gene is undetectable in resting… (More)
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