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L-798106

National Institutes of Health

Papers overview

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2017
2017
Tuberin Regulates Prostaglandin Receptor–Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells
Tuberous sclerosis complex (TSC) is a tumor-suppressor syndrome affecting multiple organs, including the brain, skin, kidneys… 
2015
2015
The EP3 Agonist Sulprostone Enhances Platelet Adhesion But Not Thrombus Formation Under Flow Conditions
Platelets express the EP2, EP3 and EP4 receptors. Prostaglandin (PG) E2 has a biphasic effect on platelets. Low concentrations of… 
2011
2011
Prostaglandin E2-prostanoid EP3 signal induces vascular contraction via nPKC and ROCK activation in rat mesenteric artery.
2011
2011
30 Investigation of the action of prostaglandin E2 on human platelets
Prostaglandin E2 (PGE2) is a product of the COX pathway and its production is believed to be elevated at sites of atherosclerotic… 
2008
2008
Investigation of the slow kinetics of the prostanoid ep3 receptor antagonists l-798106 and l-826266 on guinea-pig aorta
EP3 receptor antagonists are a recent addition to the prostanoid ligand armoury. We have examined the profiles of two such agents… 
2006
2006
Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery.
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