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L 753037

Known as: L-753,037 
 
National Institutes of Health

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J 104132

Papers overview

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2004
2004
Myocardial protection with the non-selective endothelin receptor antagonist L-753,037 following acute coronary artery occlusion in the dog.
SUMMARY Efficacy of a new, potent non-selective endothelin antagonist, l-753037, was examined in a model of canine coronary… Expand
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2000
2000
Antihypertensive effects of a mixed endothelin-A- and -B-receptor antagonist, J-104132, were augmented in the presence of an AT1 -receptor antagonist, MK-954.
The single oral administration of a mixed endothelin-A-and -B- (ETA/ETB) receptor antagonist, J-104132 (L-753,037) decreased the… Expand
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1999
1999
Teratogenic effects of the endothelin receptor antagonist L-753,037 in the rat.
The studies presented in this paper were undertaken to investigate the effects of L-753,037, a balanced endothelin receptor… Expand
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1999
1999
Pharmacological properties of J-104132 (L-753,037), a potent, orally active, mixed ETA/ETB endothelin receptor antagonist.
J-104132 [(+)-(5S,6R, 7R)-2-butyl-7-[2-((2S)-2-carboxypropyl)-4-methoxyphenyl]-5-(3, 4-methylenedioxyphenyl)cyclopenteno[1,2-b… Expand
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1999
1999
Determination of L-753,037 in human plasma by liquid chromatography/turbo ionspray tandem mass spectrometry.
A liquid chromatographic/turbo ionspray tandem mass spectrometric (LC/MS/MS) method was developed and validated for the… Expand
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