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L 703717

Known as: L 703,717, L-703,717, L-703717 
National Institutes of Health

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2 relations

Broader (2)

HydroxyquinolinesQuinolones

Papers overview

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2007
2007
Measurement of glycine binding site of N‐methyl‐d‐asparate receptors in living human brain using 4‐acetoxy derivative of L‐703,717, 4‐acetoxy‐7‐chloro‐3‐[3‐(4‐[11c] methoxybenzyl) phenyl]‐2(1H…
N‐methyl‐D‐aspartate (NMDA) receptors are of major interest in brain functions and neuropsychiatric disorders. However, at… 
2001
2001
A prodrug of NMDA/glycine site antagonist, L-703,717, with improved BBB permeability: 4-acetoxy derivative and its positron-emitter labeled analog.
4-Acetoxy derivative (1) of L-703,717, a high-affinity (IC50=4.5 nM) antagonist for the glycine site of NMDA receptors, was… 
2000
2000
A strategy for increasing the brain uptake of a radioligand in animals: use of a drug that inhibits plasma protein binding.
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