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L 627

Known as: L-627 
National Institutes of Health

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biapenem

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1998
1998
Pharmacokinetics and Safety of a New Parenteral Carbapenem Antibiotic, Biapenem (L-627), in Elderly Subjects
ABSTRACT The pharmacokinetics and tolerability of a new parenteral carbapenem antibiotic, biapenem (L-627), were studied in… 
1995
1995
Interactions of biapenem with active-site serine and metallo-beta-lactamases
Biapenem, formerly LJC 10,627 or L-627, a carbapenem antibiotic, was studied in its interactions with 12 beta-lactamases… 
1994
1994
[Pharmacokinetic and clinical studies on biapenem (L-627) in the pediatric field].
Pharmacokinetic and clinical studies on biapenem (L-627), a newly developed carbapenem, were performed and the following results… 
1994
1994
[Pharmacokinetic, bacteriological and clinical studies on biapenem (L-627) in children].
The results are summarized as follows: 1. A total of 10 patients were treated with biapenem (L-627). We received informed consent… 
1994
1994
[Effect of biapenem (L-627) on fecal flora in gnotobiotic mice and children].
Biapenem (L-627), a novel injectable carbapenem antibiotic, was studied with regard to its effect on mice inoculated with four… 
1994
1994
[Pharmacokinetic, bacteriological and clinical evaluation of biapenem (L-627) in the pediatric field].
Pharmacokinetic, bacteriological and clinical studies on biapenem (L-627), a newly developed carbapenem antibiotic, were… 
1994
1994
[Clinical evaluation of a new carbapenem antibiotic, biapenem (L-627), in the pediatric field].
Biapenem (L-627) was evaluated for its safety and efficacy in 27 children with various bacterial infections. L-627 was effective… 
1994
1994
[Bacteriological, pharmacokinetic and clinical studies on biapenem (L-627) in the pediatric field].
Antibacterial activities were determined and pharmacokinetics and a clinical studies were performed on biapenem (L-627), a novel… 
1993
1993
Phase 1 study of L-627, biapenem, a new parenteral carbapenem antibiotic.
The safety and pharmacokinetics of L-627, a new injectable carbapenem antibiotic, were evaluated in healthy volunteers. In single… 
1993
1993
Heteroaryliumthio substituted carbapenem derivatives: synthesis and in vitro activity of 1 beta-methyl-2-(dihydropyrrolotriazoliumthio)carbapenems.
The syntheses of five thiols, including three dihydropyrrolotriazoliumthiol salts, 1,4-dimethyl-5-mercaptomethyl-1,2,4-triazolium… 
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