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L-454,560

National Institutes of Health

Related topics

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1 relation

Broader (1)

Quinolines

Papers overview

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2007
2007
L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition.
2006
2006
Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560.
L-454,560 is a potent phosphodiesterase 4 (PDE4) inhibitor which was identified as a development candidate for the treatment of… 
2005
2005
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.
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