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L 374087
Known as:
L-374,087
, L-374087
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Pyridones
Sulfonamides
Papers overview
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Highly Cited
1998
Highly Cited
1998
Efficacious, orally bioavailable thrombin inhibitors based on 3-aminopyridinone or 3-aminopyrazinone acetamide peptidomimetic templates.
P. Sanderson
,
T. Lyle
,
+21 authors
J. Vacca
Journal of Medicinal Chemistry
1998
Corpus ID: 21481809
We have addressed the key deficiency of noncovalent pyridinone acetamide thrombin inhibitor L-374,087 (1), namely, its modest…
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1998
1998
C6 modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption.
R. C. Isaacs
,
K. J. Cutrona
,
+15 authors
J. Vacca
Bioorganic & Medicinal Chemistry Letters
1998
Corpus ID: 43283882
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