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L 366509

Known as: L-366,509 
 
National Institutes of Health

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2 relations

Broader (2)

PiperidinesSpiro Compounds

Papers overview

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2018
2018
Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking
The quality of social relationships is a powerful determinant of lifetime health. Here, we explored the impact of social… Expand
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1999
1999
Role of oxytocin in the initiation of term and preterm labor in rats: changes in oxytocin receptor density and plasma oxytocin concentration and the effect of an oxytocin antagonist, L-366,509.
OBJECTIVE Our purpose was to compare the functional roles of oxytocin in term and preterm labor in rats by both biochemical and… Expand
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Highly Cited
1994
Highly Cited
1994
1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin…
Modifications to the previously reported spiroindenylpiperidine camphor-sulfonamide oxytocin (OT) antagonist L-366,509 have… Expand
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1993
1993
Identification of an orally active, nonpeptidyl oxytocin antagonist.
L-366,509, a member of a novel class of nonpeptidyl compounds, has been characterized as an orally active oxytocin (OT… Expand
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1993
1993
Nanomolar-affinity, non-peptide oxytocin receptor antagonists.
Non-peptide antagonists of the peptide hormone oxytocin (OT) with nanomolar OT receptor affinities are described. These compounds… Expand
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Highly Cited
1992
Highly Cited
1992
Orally active, nonpeptide oxytocin antagonists.
The first nonpeptide antagonists of the neurohypophyseal hormone, oxytocin (OT) are described. Derivatives of the… Expand
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