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Kininogenase

Known as: Kallikreins, KLK, Kallikreins [Chemical/Ingredient] 
Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (3)

CoagulantsSerine EndopeptidasesSerine Proteases

Narrower (25)

DilminalKLK10 protein, humanKLK14 protein, humanKLK15 protein, human
Enzyme GeneHydrolysisIn BloodKallikrein.tissue type:ACnc:Pt:Plas:Qn

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1986
Review
1986
Renal kallikrein-kinin system.
In the last decade, our knowledge of the renal kallikrein-kinin system has been advanced significantly. More specific and… 
Highly Cited
1985
Highly Cited
1985
Cloning and sequence analysis of cDNAs for human high molecular weight and low molecular weight prekininogens. Primary structures of two human prekininogens.
Highly Cited
1983
Highly Cited
1983
Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement…
Review
1982
Review
1982
Dopamine and the kidney.
It would seem established beyond peradventure that dopamine is formed in the kidney from circulating L-dopa. The likely site… 
Highly Cited
1982
Highly Cited
1982
KININS STIMULATE NET CHLORIDE SECRETION BY THE RAT COLON
1 Short circuit current (SCC), transepithelial conductance and ion fluxes were measured across the isolated descending colon of… 
Highly Cited
1974
Highly Cited
1974
Urinary Kallikrein Excretion in Normal Man: Relationships to Sodium Intake and Sodium‐Retaining Steroids
The urinary excretion of kallikrein, a renal enzyme that cleaves the potent vasodilator kinin, kallidin, from kininogen, was… 
Highly Cited
1972
Highly Cited
1972
Relation between urinary kallikrein and renal function, hypertension, and excretion of sodium and water in man.
Highly Cited
1972
Highly Cited
1972
Effects of Mineralocorticoids, Altered Sodium Intake, and Adrenalectomy on Urinary Kallikrein in Rats
The urinary excretion of kallikrein was examined in rats whose mineralocorticoid level was increased by the administration of… 
Highly Cited
1969
Highly Cited
1969
Biological activities of leupeptins.
Leupeptins, leupeptin Pr and leupeptin Ac, strongly inhibit proteolysis by plasmin, trypsin and papain, but do not inhibit… 
Highly Cited
1963
Highly Cited
1963
THE NATURE OF THE KALLIDINS RELEASED FROM HUMAN PLASMA BY KALLIKREINS AND OTHER ENZYMES
The kallikreins are hypotensive enzymes of endogenous origin whose injection intravenously in very minute quantities causes a… 
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