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Kininogenase

Known as: Kallikreins, KLK, Kallikreins [Chemical/Ingredient] 
Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (3)

CoagulantsSerine EndopeptidasesSerine Proteases

Narrower (25)

DilminalKLK10 protein, humanKLK14 protein, humanKLK15 protein, human
Enzyme GeneHydrolysisIn BloodKallikrein.tissue type:ACnc:Pt:Plas:Qn

Papers overview

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Highly Cited
1985
Highly Cited
1985
Atrial natriuretic factor inhibits the hypertension induced by chronic infusion of norepinephrine in conscious rats.
To assess the physiological role of atrial natriuretic factors in the regulation of blood pressure and sodium-water excretion, we… 
Highly Cited
1982
Highly Cited
1982
Catalytic properties of serine proteases. 2. Comparison between human urinary kallikrein and human urokinase, bovine beta-trypsin, bovine thrombin, and bovine alpha-chymotrypsin.
The catalytic properties of several serine proteases acting on cationic substrates (bovine of beta-trypsin, bovine thrombin… 
Highly Cited
1980
Highly Cited
1980
Radioimmunoassay of human high molecular weight kininogen in normal and deficient plasmas.
An RIA for human HMW kininogen, capable of detecting 150 pg of antigen, has been developed. Antibody to HMW kininogen was… 
Highly Cited
1980
Highly Cited
1980
Isolation and characterization of human urinary kallikrein.
Human urinary kallikrein was purified by gel filtration on Sephacryl S-200 and affinity chromatography on aprotinin-Sepharose… 
Highly Cited
1979
Highly Cited
1979
Activation of a Prorenin‐Like Substance in Human Plasma by Trypsin and by Urinary Kallikrein
SUMMARY Inactive plasma renin (a prorenlp-like substance) can be activated by trypsin. There are also endogenous neutral serine… 
Highly Cited
1978
Highly Cited
1978
The Kallikrein‐Kinin System and Prostaglandins in the Kidney: Their Relation to Furosemide‐Induced Diuresis and to the Renin‐Angiotensin‐Aldosterone System in Man
The relations among the renin-angiotensin-aldosterone system, renal prostaglandin E, the renal kallikrein-kinin system, and… 
Highly Cited
1978
Highly Cited
1978
The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen.
1. A latent neutral proteinase was found in culture media of mouse bone explants. Its accumulation during the cultures is closely… 
Review
1978
Review
1978
Dopamine-sodium relationship: is dopamine a part of the endogenous natriuretic system?
A possible role of DA as an endogenous natriuretic hormone was reviewed under three aspects: (1) its excretion in response to… 
Highly Cited
1975
Highly Cited
1975
Factor-VIII-related antigen: multiple molecular forms in human plasma.
Analysis of Factor-VIII-related antigen (vWAg) in normal plasma by crossed immunoelectrophoresis reveals an asymmetric pattern… 
Highly Cited
1968
Highly Cited
1968
Das Kallikrein-Kinin-System und Seine Inhibitororen