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Kininogenase

Known as: Kallikreins, KLK, Kallikreins [Chemical/Ingredient] 
Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (3)

CoagulantsSerine EndopeptidasesSerine Proteases

Narrower (25)

DilminalKLK10 protein, humanKLK14 protein, humanKLK15 protein, human
Enzyme GeneHydrolysisIn BloodKallikrein.tissue type:ACnc:Pt:Plas:Qn

Papers overview

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Highly Cited
1980
Highly Cited
1980
The Antihypertensive Effect of Captopril
SUMMARY The acute effect of the orally-active converting enzyme inhibitor, captopril, was compared to that of saralasin in 13… 
Highly Cited
1980
Highly Cited
1980
Activation of membrane-bound kallikrein and renin in the kidney.
Rat kidney contains membrane-bound renin (EC 3.4.99.19) and kallikrein (EC 3.4.21.8). Kallikrein activity was measured by a… 
Highly Cited
1980
Highly Cited
1980
Radioimmunoassay of human high molecular weight kininogen in normal and deficient plasmas.
An RIA for human HMW kininogen, capable of detecting 150 pg of antigen, has been developed. Antibody to HMW kininogen was… 
Highly Cited
1979
Highly Cited
1979
Human Urinary and Plasma Kinins: Relationship to Sodium‐Retaining Steroids and Plasma Renin Activity
Sodium-retaining steroids increase urinary kallikrein but their effects on urinary kinins and plasma bradykinin are not known… 
Highly Cited
1979
Highly Cited
1979
Activation of a Prorenin‐Like Substance in Human Plasma by Trypsin and by Urinary Kallikrein
SUMMARY Inactive plasma renin (a prorenlp-like substance) can be activated by trypsin. There are also endogenous neutral serine… 
Highly Cited
1979
Highly Cited
1979
Increased Circulating Bradykinin During Hypothermia and Cardiopulmonary Bypass in Children
SUMMARYTo determine whether cold could activate the kallikrein-kinin system in vivo as it does in vitro, the circulating systemic… 
Highly Cited
1978
Highly Cited
1978
The Kallikrein‐Kinin System and Prostaglandins in the Kidney: Their Relation to Furosemide‐Induced Diuresis and to the Renin‐Angiotensin‐Aldosterone System in Man
The relations among the renin-angiotensin-aldosterone system, renal prostaglandin E, the renal kallikrein-kinin system, and… 
Highly Cited
1978
Highly Cited
1978
The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen.
1. A latent neutral proteinase was found in culture media of mouse bone explants. Its accumulation during the cultures is closely… 
Highly Cited
1975
Highly Cited
1975
Factor-VIII-related antigen: multiple molecular forms in human plasma.
Analysis of Factor-VIII-related antigen (vWAg) in normal plasma by crossed immunoelectrophoresis reveals an asymmetric pattern… 
Highly Cited
1968
Highly Cited
1968
Das Kallikrein-Kinin-System und Seine Inhibitororen