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KW 5092

Known as: KW-5092 
 
National Institutes of Health

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2 relations

Broader (2)

ImidazolesNitriles

Papers overview

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1999
1999
KW-5092, a novel gastrokinetic agent, facilitates luminal serotonin release from the guinea-pig colon.
  • S. Kojima
  • European journal of pharmacology
  • 1999
    • Corpus ID: 42786970
The present study was designed to determine the influence of KW-5092 ((1-[2-[[[5-(piperidinomethyl)-2-furanyl]methyl]amino]ethyl… Expand
1998
1998
Effects of KW‐5092 on Antroduodenal Coordination and Gastric Emptying in Guinea‐pigs
KW‐5092 (2‐[1‐[2‐[[5‐(piperidinomethyl)‐2‐furanyl]methylamino]ethyl]imidazonylidin‐2‐ylidenene]malononitrile fumarate) is a novel… Expand
1997
1997
Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood…
Acetylcholine (ACh) was detected in the blood and plasma of beagle dogs using a specific, sensitive radioimmunoassay. The mean… Expand
1995
1995
Stimulating effects of KW-5092, a novel gastroprokinetic agent, on the gastric emptying, small intestinal propulsion and colonic propulsion in rats.
KW-5092 ((1-[2-[[[5-(piperidinomethyl)-2-furanyl]methyl]amino]ethyl]- 2-imidazolidinylidene) propanedinitrile fumarate) is a… Expand
1995
1995
Enhancement of defecation and distal colonic motor activity by KW-5092, a novel gastroprokinetic agent, in rats.
KW-5092 ([1-[2-[[[5-(piperidinomethyl)-2-furanyl]- methyl]amino]ethyl]-2-imidazolidinylidene]propanedinitrile fumarate) is a… Expand
1995
1995
KW-5092, a novel gastroprokinetic agent, reverses the norepinephrine-induced decline of the gastric mucosal blood flow in rats.
We examined the effects of KW-5092 ((1-[2-[[[5-(piperidinomethyl)-2-furanyl]methyl]-amino]ethyl]- 2-imidazolidinylidene… Expand
1994
1994
Effects of KW-5092, a novel gastroprokinetic agent, on the delayed colonic propulsion in rats.
The effects of KW-5092, [1-[2-[[[5-(piperidinomethyl)-2- furanyl]methyl]amino]ethyl]-2-imidazolidinylidene]propanedinitr ile… Expand
1994
1994
Enhancement by KW-5092, a novel gastroprokinetic agent, of the gastrointestinal motor activity in dogs.
KW-5092 ([1-[2-[[[5-(piperidinomethyl)-2- furanyl]methyl]amino]ethyl]-2-imidazolidinylidene) propanedinitrile fumarate) is a… Expand
1994
1994
Inhibitory effects of KW-5092, a novel gastroprokinetic agent, on the activity of acetylcholinesterase in guinea pig ileum.
KW-5092 ([1-[2-[[[5-(piperidinomethyl)-2- furanyl]methyl]amino]ethyl]-2-imidazolidinylidene] propanedinitrile fumarate) is a… Expand
1994
1994
Enhancement by KW-5092, a novel gastroprokinetic agent, of the release of acetylcholine from enteric neurons in the guinea pig ileum.
KW-5092 ((1-[2-[[[5-(piperidinomethyl)-2-furanyl]methyl]amino]ethyl]-2- imidazolidinylidene) propanedinitrile fumarate) is a… Expand
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