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KSR2 gene

Known as: Kinase Suppressor of Ras 2 Gene, KINASE SUPPRESSOR OF RAS 2, KSR2 
This gene plays a role in the regulation of MAP kinase kinase activity.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Many cancers, including those of the colon, lung, and pancreas, depend upon the signaling pathways induced by mutated and… Expand
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2016
2016
Individuals with poor postnatal growth are at risk for cardiovascular and metabolic problems as adults. Here we show that… Expand
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2015
2015
The metabolic syndrome (MetS) is a constellation of metabolic disorders that increase the risk of developing several diseases… Expand
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Highly Cited
2013
Highly Cited
2013
Kinase suppressor of Ras 2 (KSR2) is an intracellular scaffolding protein involved in multiple signaling pathways. Targeted… Expand
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2013
2013
MicroRNA (miRNA) has an important role as a master regulator of gene expression in immune system and is upregulated during T cell… Expand
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2012
2012
Kinase suppressor of Ras 1 (KSR1) and KSR2 are scaffolds that promote extracellular signal-regulated kinase (ERK) signaling but… Expand
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2011
2011
The kinase suppressor of ras 2 (KSR2) gene resides at human chromosome 12q24, a region linked to obesity and type 2 diabetes (T2D… Expand
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Highly Cited
2009
Highly Cited
2009
Kinase suppressors of Ras 1 and 2 (KSR1 and KSR2) function as molecular scaffolds to potently regulate the MAP kinases ERK1/2 and… Expand
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Highly Cited
2009
Highly Cited
2009
Protein scaffolds have emerged as important regulators of MAPK cascades, facilitating kinase activation and providing crucial… Expand
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2008
2008
We developed a high-throughput approach to knockout (KO) and phenotype mouse orthologs of the 5,000 potential drug targets in the… Expand
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