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KSR protein, human

Known as: Kinase Suppressor of Ras, Kinase Suppressor of RAS-1, KSR Protein 
Similar to RAS kinase suppressor (Drosophila) and encoded by human KSR Gene (SER/THR PK Family), Kinase Suppressor of RAS-1 is a positive modulator… 
National Institutes of Health

Related topics

Related topics

12 relations
Ceramide Signaling Pathway PIDCytoplasmDAG/PE-Binding DomainHomo sapiens

Broader (1)

Kinase suppressor of ras-1 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Poly vinyl acetate and ammonio methacrylate copolymer as unconventional polymer blends increase the mechanical robustness of HPMC matrix tablets.
2016
2016
Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies
In response to stimuli, biological processes are tightly controlled by dynamic cellular signaling mechanisms. Reversible protein… 
Review
2013
Review
2013
A pickup in pseudokinase activity.
Kinases catalyse the phosphorylation of target substrates on hydroxy group-containing residues as a means to nucleate multi… 
Highly Cited
2011
Highly Cited
2011
The oncogenetic role of microRNA-31 as a potential biomarker in oesophageal squamous cell carcinoma.
miR-31 (microRNA-31) is frequently altered in numerous cancers. The aim of the present study was to investigate the role of miR… 
2011
2011
Simulating EGFR-ERK Signaling Control by Scaffold Proteins KSR and MP1 Reveals Differential Ligand-Sensitivity Co-Regulated by Cbl-CIN85 and Endophilin
ERK activation is enhanced by the scaffolding proteins KSR and MP1, localized near the cell membrane and late endosomes… 
2009
2009
A Ceramide-binding C1 Domain Mediates Kinase Suppressor of Ras Membrane Translocation
Genetic and biochemical data support Kinase Suppressor of Ras 1 (KSR1) as a positive regulator of the Ras-Raf-MAPK pathway… 
Highly Cited
2006
Highly Cited
2006
A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.
RAF is a critical effector of the small GTPase RAS in normal and malignant cells. Despite intense scrutiny, the mechanism… 
2004
2004
Improved Generation of C 57 BL / 6 J Mouse Embryonic Stem Cells in a Defined Serum-Free Media
C57BL/6 is a well-characterized mouse strain that is used extensively for immunological and neurological research. The… 
Highly Cited
2000
Highly Cited
2000
A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.
kinase suppressor of Ras (ksr) encodes a putative protein kinase that by genetic criteria appears to function downstream of RAS… 
Highly Cited
1997
Highly Cited
1997
The protein kinase KSR interacts with 14-3-3 protein and Raf
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