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KRT1 gene

Known as: keratin 1, KRT1, K1 
This gene is involved in skin development.
National Institutes of Health

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Related topics

15 relations
Cell MovementCytokeratinCytokeratin test systemCytokinesis
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KRT1 wt Allele

Papers overview

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2015
2015
Frequent somatic reversion of KRT1 mutations in ichthyosis with confetti.
Widespread reversion of genetic disease is rare; however, such events are particularly evident in some skin disorders in which… Expand
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2007
2007
Myeloperoxidase interacts with endothelial cell-surface cytokeratin 1 and modulates bradykinin production by the plasma Kallikrein-Kinin system.
During an inflammatory state, functional myeloperoxidase (MPO) is released into the vessel as a result of intravascular… Expand
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Highly Cited
2006
Highly Cited
2006
Allele-Specific KRT1 Expression Is a Complex Trait
The differential expression of alleles occurs commonly in humans and is likely an important genetic factor underlying heritable… Expand
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Highly Cited
2004
Highly Cited
2004
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.
In resting cells, the NFAT1 transcription factor is kept inactive in the cytoplasm by phosphorylation on multiple serine residues… Expand
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Highly Cited
2002
Highly Cited
2002
Factor XII interacts with the multiprotein assembly of urokinase plasminogen activator receptor, gC1qR, and cytokeratin 1 on endothelial cell membranes.
Investigations were performed to define the factor XII (FXII) binding site(s) on cultured endothelial cells (HUVECs). Biotin- or… Expand
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Review
2002
Review
2002
Assembly and activation of the plasma kallikrein/kinin system: a new interpretation.
Understanding the importance and physiologic activity of the plasma kallikrein/kinin system (KKS) has been thwarted by the… Expand
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Review
2002
Review
2002
The plasma kallikrein-kinin system counterbalances the renin-angiotensin system.
The plasma kallikrein-kinin system (KKS), first recognized over 40 years ago, was originally believed to contribute to… Expand
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Highly Cited
2001
Highly Cited
2001
Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1.
Oxidative stress increases endothelial mannose-binding lectin (MBL) binding and activates the lectin complement pathway (LCP… Expand
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2001
2001
Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells.
The cellular localization of human cytokeratin 1 (CK1), urokinase plasminogen activator receptor (uPAR), and gC1qR, high… Expand
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1994
1994
Mutations in the H1 and 1A domains in the keratin 1 gene in epidermolytic hyperkeratosis.
In the autosomal dominant disorder epidermolytic hyperkeratosis, the structural integrity of the keratin intermediate filaments… Expand
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