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KRP-203

Known as: 2-Amino-2-propanediol Hydrochloride, KRP203, S1P Receptor Agonist KRP203 
The hydrochloride salt form of 2-amino-2 propanediol (KRP-203), a sphingosine 1-phosphate (S1P) receptor agonist, with potential immunosuppressive… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming… Expand
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Highly Cited
2013
Highly Cited
2013
Sphingosine-1-phosphate (S1P) is a pluripotent lipophilic mediator working as a ligand for G-protein coupled S1P receptors (S1PR… Expand
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2013
2013
Objective—Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins. We… Expand
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2013
2013
Objective—Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins. We… Expand
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Highly Cited
2008
Highly Cited
2008
Current treatments for patients with Crohn's disease (CD) are based on recent advances in elucidating the pathophysiology of the… Expand
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2007
2007
Sphingosine-1-phosphate (S1P) is an active sphingolipid metabolite that exerts important biological effects. Recently, we… Expand
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2006
2006
Background. We demonstrate the long-term effectiveness of KRP-203 treatment in combination with a subtherapeutic dose of… Expand
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2006
2006
BACKGROUND To explore a more effective and less toxic immunosuppressive strategy in organ transplantation, we recently developed… Expand
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Highly Cited
2005
Highly Cited
2005
Background—A novel immunomodulator, KRP-203, the molecular structure of which has some similarity to FTY720, has been developed… Expand
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2005
2005
To find more effective and less toxic immunosuppressive strategies in long-term treatment for organ transplantation patients, we… Expand
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