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KRAS NP_004976.2:p.G13X
Known as:
GTPase KRas G13X
, KRAS G13 Mutation
, KRAS p.Gly13Xxx
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A change in the amino acid residue at position 13 in the GTPase KRas protein where glycine has been replaced by another amino acid.
National Institutes of Health
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Related topics
1 relation
Kras gene mutation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Benefit of cetuximab addition to a platinum–fluorouracil-based chemotherapy according to KRAS-LCS6 variant in an unselected population of recurrent and/or metastatic head and neck cancers
V. Bastit
,
N. Bon‐Mardion
,
+10 authors
F. Clatot
European Archives of Oto-Rhino-Laryngology
2018
Corpus ID: 54448120
ObjectivesTo evaluate the benefit of cetuximab (Cx) addition to platinum-based and 5-fluorouracil chemotherapy (PFU) in…
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Review
2017
Review
2017
Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90
M. Magnetta
,
A. Ghodadra
,
Steven J. Lahti
,
M. Xing
,
Di Zhang
,
H. S. Kim
Abdominal Radiology
2017
Corpus ID: 3981630
PurposeTo determine whether pathologic colorectal tumor KRAS mutation status is correlated with progression-free survival (PFS…
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2012
2012
KRAS mutation detection by high-resolution melting analysis significantly predicts clinical benefit of cetuximab in metastatic colorectal cancer
U. Malapelle
,
C. Carlomagno
,
+8 authors
G. Troncone
British Journal of Cancer
2012
Corpus ID: 5855038
Background:Anti-epidermal growth factor receptor (EGFR) monoclonal antibodies are restricted to KRAS wild-type (WT) metastatic…
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2012
2012
Influence of KRAS mutation status in metachronous and synchronous metastatic colorectal adenocarcinoma
J. Rose
,
D. Serna
,
+5 authors
T. Bekaii-Saab
Cancer
2012
Corpus ID: 23383682
Mutations in the v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) are present in approximately 30% to 40% of…
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2011
2011
Tumor KRAS status predicts responsiveness to panitumumab in Japanese patients with metastatic colorectal cancer.
T. Doi
,
M. Tahara
,
+7 authors
Daisuke Asahi
Japanese Journal of Clinical Oncology
2011
Corpus ID: 6018029
OBJECTIVE Mutation status of the KRAS gene in tumors has been shown to be a predictive biomarker of response to anti-epidermal…
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2010
2010
Comparative analysis of dideoxy sequencing, the KRAS StripAssay and pyrosequencing for detection of KRAS mutation.
Jing Gao
,
Yanyan Li
,
Ping Sun
,
L. Shen
World Journal of Gastroenterology
2010
Corpus ID: 34142102
AIM To compare the differences between dideoxy sequencing/KRAS StripAssay/pyrosequencing for detection of KRAS mutation in…
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2009
2009
[Validation study of KRAS mutation in colorectal cancer].
László Kopper
,
J. Tímár
Magyar Onkológia
2009
Corpus ID: 116562326
There is no doubt that molecular targeted therapy has increasing importance in clinical oncology. Markers related to the…
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2009
2009
DUSPs as markers of MEK/Erk activation in primary colorectal cancer.
W. De Roock
,
M. Janssens
,
+5 authors
S. Tejpar
Journal of Clinical Oncology
2009
Corpus ID: 9242742
4064 Background: DUSPs dephosphorylate P-MAPK and are activated as a negative feedback loop upon RTK signaling. Higher expression…
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2009
2009
Correlation of KRAS status with clinical outcome in patients (pts) with metastatic colorectal cancer (mCRC) treated first-line with FOLFOX6 + cetuximab (FX+C) or FOLFIRI + cetuximab (FF+C): The CECOG…
I. Koza
,
F. Wrba
,
+7 authors
T. Brodowicz
Journal of Clinical Oncology
2009
Corpus ID: 21554672
4055 Background: Previous retrospective analyses of KRAS mutation status from the randomized CECOG/CORE 1.2.001 phase II trial…
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1998
1998
Molekulargenetik der epithelialen Ovarialneoplasien: Korrelationen zum Phänotyp und biologischen Verhalten
J. Diebold
Der Pathologe
1998
Corpus ID: 23848405
ZusammenfassungDie phänotypischen Unterschiede zwischen den verschiedenen Formen der epithelialen Ovarialneoplasien haben…
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