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KR-32568

National Institutes of Health

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Guanidines

Papers overview

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2012
2012
Persistent sodium current and Na+/H+ exchange contributes to the augmentation of the reverse Na+/Ca2+ exchange during hypoxia or acute ischemia in ventricular myocytes
The increases in persistent sodium currents (INa.P) and Na+/H+ exchange (NHE) causes intracellular Ca2+ overload. The objective… 
2011
2011
Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
Intracellular pH (pHi) is an important endogenous modulator of cardiac function. Inhibition of Na+/H+ exchanger-1 (NHE-1… 
2005
2005
Cardioprotective Effects of [5-(2-Methyl-5-Fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an Anesthetized Rat Model of Ischemia and Reperfusion Heart Injury
The effects of a novel sodium/hydrogen exchanger-1 (NHE-1) inhibitor, KR-32568, were studied in an anesthetized rat model of 30… 
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