KPT-251
National Institutes of Health
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Background and aimsIncreased expression of Chromosome Region Maintenance (CRM-1)/exportin-1 (XPO-1) has been correlated with poor…
Increased expression of Chromosome Region Maintenance (CRM-1)/exportin-1 (XPO-1) has been correlated with poor prognosis in…
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC
Background: CRM1 (XPO1) is the exclusive exportin…
Resistance to BRAF inhibitor therapy places priority on developing BRAF inhibitor-based combinations that will overcome de novo…
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL
Recent evidence demonstrates that Non Hodgkin's…
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL
CRM-1 exportin protein encoded by the XPO-1 gene…
Drugs that target the chief mediator of nuclear export, chromosome region maintenance 1 protein (CRM1) have potential as…
Abstract 598 Recent evidence demonstrates that Non Hodgkin9s Lymphoma (NHL) tumors have elevated expression of the XPO1 gene that…