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KP-1019

Known as: KP 1019, KP1019 
National Institutes of Health

Papers overview

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2020
2020
Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019.
Like platinum-based chemotherapeutics, the anticancer ruthenium complex indazolium trans-[tetrachlorobis(1H-indazole)ruthenate… 
Review
2018
Review
2018
The Deceptively Similar Ruthenium(III) Drug Candidates KP1019 and NAMI-A Have Different Actions. What Did We Learn in the Past 30 Years?
The general interest in anticancer metal-based drugs and some encouraging pharmacological results obtained at the beginning of… 
2018
2018
Studies of KP46 and KP1019 and the Hydrolysis Product of KP1019 in Lipiodol Emulsions: Preparation and Initial Characterizations as Potential Theragnostic Agents.
BACKGROUND Lipiodol (iodized poppy seed oil) accumulates predominately in the tumor rather than in the liver tissue [1, 2… 
2016
2016
Comparison of KP1019 and NAMI-A in tumour-mimetic environments.
NAMI-A and KP1019 are Ru(III)-based anti-metastatic and cytotoxic anti-cancer drugs, respectively, and have been proposed to be… 
2015
2015
Inhibitory effects of NAMI-A-like ruthenium complexes on prion neuropeptide fibril formation.
Prion diseases are a group of infectious and fatal neurodegenerative disorders caused by the conformational conversion of a… 
2013
2013
Computational study on ruthenium anticancer complexes in the presence of Reactive Oxygen Species
Diese Masterarbeit behandelt die Reduktions-Oxidationschemie von Rutheniumkomplexen in der Gegenwart von reaktiven… 
2012
2012
Novel ruthenium nitrosyl complexes with azole heterocycles and osmium(IV) analogues of KP1019 as potential anticancer drugs
2011
2011
Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019
Ascorbic acid has been previously discussed to have antitumor potential through its interaction with transition metal ions such… 
Highly Cited
2005
Highly Cited
2005
Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells
Purpose The ruthenium complex salt indazolium trans-[tetrachlorobisindazole-ruthenate(III)] (KP1019) and the analogous sodium… 
2004
2004
630 Molecular mechanisms of resistance against the ruthenium compound KP1019
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