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KOS-1803

National Institutes of Health

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Iso-fludelone

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2008
2008
Iso-oxazole-Fludelone (KOS-1803) as a potent and efficacious microtubule-stablization epothilone against xenograft tumors.
1402 17-Iso-oxazole-26-F3-9,10-dehydro-12,13-desoxy-epothilone B (Iso-Fludelone or KOS-1803) designed by diverted total synthesis… 
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