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KNI-727

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2009
0120012009

Related topics

Related topics

1 relation

Broader (1)

Thiazoles

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
KNI-727
Thiazoles

Papers overview

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2009
2009
Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.
A series of HIV protease inhibitor based on the allophenylnorstatine structure with various P(2)' moieties were synthesized… (More)
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2004
2004
Water-soluble prodrugs of dipeptide HIV protease inhibitors based on O-->N intramolecular acyl migration: Design, synthesis and kinetic study.
To improve the low water-solubility of HIV protease inhibitors, we synthesized water-soluble prodrugs of KNI-727, a potent small… (More)
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2003
2003
Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical…
We designed and synthesized a series of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727 (1), which is a sparingly… (More)
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2002
2002
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.
Plasmepsin II is a key enzyme in the life cycle of the Plasmodium parasites responsible for malaria, a disease that afflicts more… (More)
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2001
2001
Controlled drug release: new water-soluble prodrugs of an HIV protease inhibitor.
We designed and synthesized a series of highly water-soluble prodrugs of an HIV protease inhibitor, KNI-727 (1), containing… (More)
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