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KNI-727

National Institutes of Health

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Broader (1)

Thiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.
A series of HIV protease inhibitor based on the allophenylnorstatine structure with various P(2)' moieties were synthesized… 
2005
2005
Evidence for the cellular uptake of anti-HIV-1 double drug KNI-1039
Combination therapy, or highly active antiretroviral therapy (HAART) comprising at least three anti-HIV drugs, nucleoside… 
2004
2004
Water-soluble prodrugs of dipeptide HIV protease inhibitors based on O-->N intramolecular acyl migration: Design, synthesis and kinetic study.
2003
2003
Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical…
We designed and synthesized a series of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727 (1), which is a sparingly… 
Highly Cited
2002
Highly Cited
2002
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.
Plasmepsin II is a key enzyme in the life cycle of the Plasmodium parasites responsible for malaria, a disease that afflicts more… 
2001
2001
Controlled drug release: new water-soluble prodrugs of an HIV protease inhibitor.
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