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KN 04

Known as: KN-04 
National Institutes of Health

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1 relation
analogs & derivatives

Papers overview

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Review
2007
Review
2007
Molecular probes for P2X7 receptor studies.
The ionotropic P2X7 receptor (P2X7R) has become the focus of intense research interest for a number of reasons: i) it is a cation… 
2005
2005
Type-3 ryanodine receptor involved in Ca2+-induced Ca2+ release and transmitter exocytosis at frog motor nerve terminals.
2001
2001
Differential effects of chronic drug treatment on alpha3* and alpha7 nicotinic receptor binding sites, in hippocampal neurones and SH-SY5Y cells.
1. The aim of this study was to compare the effects of chronic treatment (for 4 or 7 days) with nicotinic drugs and 20 mM KCl on… 
2001
2001
Regulation of Kv1.3 Channels in Activated Human T Lymphocytes by Ca2+-Dependent Pathways
Activated T lymphoblasts respond more effectively to mitogenic stimuli than resting T cells, partly through differences in Ca2… 
2000
2000
Ca2+/Calmodulin‐Mediated Regulation of the Desensitizing Process in Gq Protein‐Coupled Histamine H1 Receptor‐Mediated Ca2+ Responses in Human U373 MG Astrocytoma Cells
We investigated Ca2+/calmodulin (CaM)‐mediated regulation of the desensitizing process of the histamine H1 receptor‐mediated… 
1999
1999
1-[N, O-bis-(5-isoquinolinesulphonyl)-N-methyl-L-tyrosyl]-4- phenylpiperazine (KN-62), an inhibitor of calcium-dependent camodulin protein kinase II, inhibits both insulin- and hypoxia-stimulated…
Previous studies have indicated a role for calmodulin in hypoxia-and insulin-stimulated glucose transport. However, since… 
1996
1996
Effects of Protein Kinase Inhibitors on Morphology and Function of Cultured Bovine Adrenal Chromaffin Cells: KN‐62 Inhibits Secretory Function by Blocking Stimulated Ca2+ Entry
Abstract: In cultured bovine adrenal chromaffin cells, a nonselective protein kinase inhibitor, staurosporine, inhibits secretory… 
1996
1996
Ca2+/Calmodulin‐Dependent Protein Kinase II Inhibitor KN‐62 Inhibits Adrenal Medullary Chromaffin Cell Functions Independent of Its Action on the Kinase
Abstract: KN‐62, an inhibitor of Ca2+/calmodulin‐dependent protein kinase II (CaM kinase II), inhibited significantly… 
1994
1994
Ca2+/calmodulin-dependent regulation of the density of Na+ channels in embryonic chick skeletal muscle cells during their development in culture.
Regulation of the density of voltage-dependent Na+ channels (VDNC) was studied in chick myotubes during their development in… 
1992
1992
Inhibition of insulin secretion by KN-62, a specific inhibitor of the multifunctional Ca2+/calmodulin-dependent protein kinase II.
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