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KMT5C gene

Known as: lysine methyltransferase 5C, MGC2705, SUPPRESSOR OF VARIEGATION 4-20, DROSOPHILA, HOMOLOG OF, 2 
This gene is involved in epigenetic control of gene expression.
National Institutes of Health

Papers overview

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2019
2019
Breast cancer is the most prevalent cancer in women worldwide, which remains incurable once metastatic. Breast cancer stem cells… Expand
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2017
2017
Protein lysine methyltransferases (PKMTs) regulate diverse physiological processes including transcription and the maintenance of… Expand
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2016
2016
BackgroundHistone modification H4K20me3 and its methyltransferase SUV420H2 have been implicated in suppression of tumorigenesis… Expand
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2014
2014
Background: MSL-mediated H4K16Ac allows release from Pol II promoter-proximal pausing, and SUV420H2-mediated H4K20me3 enforces… Expand
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2013
2013
IntroductionLoss of histone H4 lysine 20 trimethylation (H4K20me3) is associated with multiple cancers, but its role in breast… Expand
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2013
2013
SUV420H1 and SUV420H2 are two highly homologous enzymes that methylate lysine 20 of histone H4 (H4K20), a mark that has been… Expand
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2011
2011
Epigenetic biomarkers are emerging as determinants of breast cancer prognosis. Breast cancer cells display unique alterations in… Expand
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2010
2010
BACKGROUND Methylation of histone H4 on lysine 20 plays critical roles in chromatin structure and function via mono- (H4K20me1… Expand
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2009
2009
BackgroundHistone lysine methylation plays a fundamental role in chromatin organization and marks distinct chromatin regions. In… Expand
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2005
2005
Genome-wide scans have mapped economically important quantitative trait loci (QTL) for mastitis susceptibility in dairy cattle at… Expand
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