KMT5C gene

Known as: lysine methyltransferase 5C, MGC2705, SUPPRESSOR OF VARIEGATION 4-20, DROSOPHILA, HOMOLOG OF, 2 
This gene is involved in epigenetic control of gene expression.

Topic mentions per year

Topic mentions per year

2005-2017
01220052017

Papers overview

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2017
2017
Protein lysine methyltransferases (PKMTs) regulate diverse physiological processes including transcription and the maintenance of… (More)
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2016
2016
Histone modification H4K20me3 and its methyltransferase SUV420H2 have been implicated in suppression of tumorigenesis. The… (More)
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2015
2015
The genome-wide loss of histone H4 lysine 20 tri-methylation (H4K20me3) is observed in multiple types of cancer, including breast… (More)
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2014
2014
RNA polymerase II (Pol II) promoter-proximal pausing plays a critical role in postinitiation transcriptional regulation at many… (More)
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2013
2013
Loss of histone H4 lysine 20 trimethylation (H4K20me3) is associated with multiple cancers, but its role in breast tumors is… (More)
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2013
2013
SUV420H1 and SUV420H2 are two highly homologous enzymes that methylate lysine 20 of histone H4 (H4K20), a mark that has been… (More)
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2012
2012
Post-translational modifications (PTMs) of histones and other proteins are perturbed in tumours. For example, reduced levels of… (More)
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2011
2011
Epigenetic biomarkers are emerging as determinants of breast cancer prognosis. Breast cancer cells display unique alterations in… (More)
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2009
2009
Histone lysine methylation plays a fundamental role in chromatin organization and marks distinct chromatin regions. In particular… (More)
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2005
2005
Genome-wide scans have mapped economically important quantitative trait loci (QTL) for mastitis susceptibility in dairy cattle at… (More)
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