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KMT5B gene

Known as: CGI85, CGI-85, SUV420H1 
This gene is involved in epigenetic control of gene expression.
National Institutes of Health

Papers overview

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2018
2018
The failure to develop effective therapies for pediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in… Expand
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2017
2017
Protein lysine methyltransferases (PKMTs) regulate diverse physiological processes including transcription and the maintenance of… Expand
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Highly Cited
2015
Highly Cited
2015
Histone lysine methyltransferases (HMTs), a large class of enzymes that catalyze site-specific methylation of lysine residues on… Expand
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2015
2015
A number of recent studies have investigated the role of de novo mutations in various neurodevelopmental and neuropsychiatric… Expand
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Highly Cited
2013
Highly Cited
2013
IntroductionLoss of histone H4 lysine 20 trimethylation (H4K20me3) is associated with multiple cancers, but its role in breast… Expand
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Highly Cited
2013
Highly Cited
2013
Glycosylation of immunoglobulin G (IgG) influences IgG effector function by modulating binding to Fc receptors. To identify… Expand
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2013
2013
SUV420H1 and SUV420H2 are two highly homologous enzymes that methylate lysine 20 of histone H4 (H4K20), a mark that has been… Expand
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2010
2010
Background Methylation of histone H4 on lysine 20 plays critical roles in chromatin structure and function via mono- (H4K20me1… Expand
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Highly Cited
2008
Highly Cited
2008
Lethal 3 malignant brain tumor 1 (L3MBTL1), a homolog of the Drosophila polycomb tumor suppressor l(3)mbt, contains three tandem… Expand
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2001
2001
Type 1 diabetes is a complex disorder with interaction of both genetic and environmental factors. One of the loci, IDDM4, has… Expand
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