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KMT2B gene

Known as: LYSINE-SPECIFIC METHYLTRANSFERASE 2B, KMT2B, HRX2 
This gene is involved in both histone methylation and transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now known to be critical in the regulation of… Expand
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2017
2017
Kmt2a and Kmt2b are H3K4 methyltransferases of the Set1/Trithorax class. We have recently shown the importance of Kmt2b for… Expand
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2017
2017
BACKGROUND Recently a novel syndrome of childhood-onset generalized dystonia originating from mutations in lysine-specific… Expand
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Highly Cited
2016
Highly Cited
2016
Early-onset generalized dystonia represents the severest form of dystonia, a hyperkinetic movement disorder defined by… Expand
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Highly Cited
2016
Highly Cited
2016
Significance Transcriptional enhancers control cell-identity gene expression and thus determine cell identity. Enhancers are… Expand
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Highly Cited
2013
Highly Cited
2013
The consolidation of long-term memories requires differential gene expression. Recent research has suggested that dynamic changes… Expand
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2013
2013
Tet proteins are emerging as major epigenetic modulators of cell fate and plasticity. However, little is known about how Tet… Expand
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2013
2013
ABSTRACT KMT2B (MLL2/WBP7) is a member of the MLL subfamily of H3K4-specific histone lysine methyltransferases (KMT2) and is… Expand
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Highly Cited
2008
Highly Cited
2008
Integration of hepatitis B virus (HBV) DNA into host DNA is detected in about 90% of HBV-related hepatocellular carcinoma (HCC… Expand
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Highly Cited
1997
Highly Cited
1997
Thioredoxin (Trx) is a small ubiquitous protein that displays different functions mainly via redox-mediated processes. We here… Expand
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