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KLK10 wt Allele

Known as: PRSSL1, Breast Normal Epithelial Cell Associated Serine Protease Gene, NES1 
Human KLK10 wild-type allele is located in the vicinity of 19q13 and is approximately 7 kb in length. This allele, which encodes kallikrein-10… 
National Institutes of Health

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Related topics

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19q13HydrolysisProteolysis

Broader (1)

KLK10 gene

Papers overview

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2015
2015
Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development
The oligodendrocyte transcription factor Olig1 is critical for both oligodendrocyte development and remyelination in mice… 
Highly Cited
2012
Highly Cited
2012
A Second CRM1-Dependent Nuclear Export Signal in the Influenza A Virus NS2 Protein Contributes to the Nuclear Export of Viral Ribonucleoproteins
ABSTRACT Influenza A virus NS2 protein, also called nuclear export protein (NEP), is crucial for the nuclear export of viral… 
2006
2006
Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of β-catenin
The human Kank protein has a role in controlling the formation of the cytoskeleton by regulating actin polymerization. Besides… 
Highly Cited
2005
Highly Cited
2005
Downregulation of Human Kallikrein 10 (KLK10/NES1) by CpG Island Hypermethylation in Breast, Ovarian and Prostate Cancers
Objective: The human kallikrein 10 (KLK10)/normal epithelial cell-specific-1 (NES1) gene is highly expressed in normal mammary… 
2004
2004
Nuclear export of alpha-catenin: overlap between nuclear export signal sequences and the beta-catenin binding site.
Mutations in APC or in beta-catenin, which are common in colon cancer, lead to constitutive activation of beta-catenin/Tcf… 
Highly Cited
2001
Highly Cited
2001
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression.
The normal epithelial cell-specific-1 (NES1)/kallikrein 10 gene is expressed in normal mammary epithelial cells, but its… 
Highly Cited
2001
Highly Cited
2001
Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue
The normal epithelial cell-specific 1 (NES1) gene (official name kallikrein gene 10; KLK10) is a new member of the expanding… 
Highly Cited
2001
Highly Cited
2001
Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer.
PURPOSE Normal epithelial cell specific-1 (NES1)/kallikrein 10 gene is expressed in normal mammary and prostate epithelial cells… 
Highly Cited
1998
Highly Cited
1998
The role for NES1 serine protease as a novel tumor suppressor.
Previously (Liu et al, Cancer Res., 56: 3371-3379, 1996), we isolated a novel serine protease-like gene--Normal Epithelial Cell… 
Highly Cited
1994
Highly Cited
1994
Neurobehavioral and neurophysiological observations in six year old children with low lead levels in East and West Germany.
Within a larger comparative environmental health screening program in East and West Germany neurobehavioral and… 
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