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KLK10 wt Allele

Known as: PRSSL1, Breast Normal Epithelial Cell Associated Serine Protease Gene, NES1 
Human KLK10 wild-type allele is located in the vicinity of 19q13 and is approximately 7 kb in length. This allele, which encodes kallikrein-10… 
National Institutes of Health

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19q13HydrolysisProteolysis

Broader (1)

KLK10 gene

Papers overview

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2019
2019
NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation inhibition
NES1 gene is thought to be a tumor-suppressor gene. Our previous study found that overexpression of NES1 gene in PC3 cell line… 
2016
2016
Screening and analysis of breast cancer genes regulated by the human mammary microenvironment in a humanized mouse model.
Tumor microenvironments play critical regulatory roles in tumor growth. Although mouse cancer models have contributed to the… 
2012
2012
Expression and clinical significance of NES1 gene in hepatocellular carcinoma
Objective To investigate effect of NES1 gene in HCC.Methods RT-PCR was employed todetermine the mRNA expression of NES1mRNA in 30… 
2008
2008
Suppression of gastric cancer growth by baculovirus vector-mediated transfer of normal epithelial cell specific-1 gene.
AIM To study the inhibitory effect of baculovirus-mediated normal epithelial cell specific-1 (NES1) gene therapy on gastric… 
2007
2007
Demethylation treatment of NES1 gene for breast carcinoma xenografted in nude mice
Objective To study the anti-tumor effect of 5-aza-2′-deoxycytidine(5-aza-dC) on breast carcinoma xenografted in nude mice… 
2006
2006
The Role for NES 1 Serine Protease as a Novel Tumor Suppressor 1
Previously (Liu et al, Cancer Res., 56: 3371-3379, 1996), we isolated a novel serine protease-like gene—Normal Epithelial Cell… 
2005
2005
Epigenetic modification regulates the expression of NES1 gene in human gastric cancer cell lines
Objective To investigate the normal epithelial cell specific1,1 (NES1) gene expression and the methylation of NES1 gene CpG… 
2004
2004
Nuclear export of alpha-catenin: overlap between nuclear export signal sequences and the beta-catenin binding site.
Mutations in APC or in beta-catenin, which are common in colon cancer, lead to constitutive activation of beta-catenin/Tcf… 
2004
2004
mRNA expression of apoptosis-associated genes in infant acute lymphoblastic leukemia: low Fas expression is an independent predictor for poor prognosis
mRNA expression of apoptosis-associated genes in infant acute lymphoblastic leukemia: low Fas expression is an independent… 
2001
2001
Loss of expression of a novel tumor suppressor gene, NES1, as an early marker for infiltrating ductal carcinoma of the breast
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