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KLHL1 gene

Known as: kelch like family member 1, Kelch-like protein 1, MRP2 
National Institutes of Health

Related topics

Related topics

6 relations
KLHL10 geneKLHL11 geneKLHL12 geneKLHL15 gene

Papers overview

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2015
2015
Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples.
Anastrozole is an aromatase inhibitor (AI) used as adjuvant therapy for breast cancer. Anastrozole is subject to direct… 
2015
2015
Acetaminophen toxicity up-regulates MRP2 expression in the liver of cats: an old story with new vision
Abstract This study was conducted to clarify the role of efflux transporter MRP2 in acetaminophen-induced hepatotoxicity in cats… 
2015
2015
[The evaluation of efflux transporter model based on RNA interference technology in vitro].
In the present study, the specifically knockdown models of P-gp or MRP2 were constructed by using a series of chemically… 
2014
2014
“Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183”
SummaryBMS-275,183 is a novel oral C-4 methyl carbonate analogue of paclitaxel. Recently, a drug-drug interaction between BMS-275… 
2013
2013
Abstract 966: Effect of ABC drug transporters (BCRP, MDR1, MRP2) on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form…
In our studies we explore whether barasertib (AZD1152), a novel Aurora B kinase inhibitor, and its more active form barasertib… 
2011
2011
Chalcogenopyrylium Dyes as Modulators of Multidrug Resistance Protein (MRP) 1
Thesis (Master, Pathology & Molecular Medicine) -- Queen's University, 2011-11-28 17:50:49.432 
2008
2008
Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver
Moxifloxacin is a novel antibacterial agent that undergoes extensive metabolism in the liver to the glucuronide M1 and the… 
2008
2008
Antiepileptic Drug Transport—Of Mice and Men
Differences in the Transport of the Antiepileptic Drugs Phenytoin, Levetiracetam and Carbamazepine by Human and Mouse P… 
2003
2003
Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells.
Rat multidrug resistant protein 2 (Mrp2; Abcc2), an ATP-driven pump located on the canalicular domain of hepatocytes, exports… 
2002
2002
Perspectives in Pharmacology Sponsored by the Drug Metabolism Division Regulation of Expression of the Multidrug Resistance-Associated Protein 2 ( MRP 2 ) and Its Role in Drug Disposition
The multidrug resistance protein 2 (MRP2; ABCC2) is an ATPbinding cassette transporter accepting a diverse range of substrates… 
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