KLF1 gene

Known as: EKLF, Kruppel-like factor 1 (erythroid), KRUPPEL-LIKE FACTOR 1 
This gene is involved in both transcriptional regulation and erythrocyte differentiation.
National Institutes of Health

Papers overview

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2012
2012
Variations at the KLF1 gene have been associated with a series of human erythroid phenotypes including the In-(Lu) phenotype… (More)
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2011
2011
Increased hemoglobin A(2) (HbA(2); ie, levels > 3.9%) is the most important feature of β-thalassemia carriers. However, it is not… (More)
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Highly Cited
2010
Highly Cited
2010
We show that knockdown of KLF1 in human and mouse adult erythroid progenitors markedly reduces BCL11A levels and increases human… (More)
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Highly Cited
2010
Highly Cited
2010
Hereditary persistence of fetal hemoglobin (HPFH) is characterized by persistent high levels of fetal hemoglobin (HbF) in adults… (More)
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Highly Cited
2010
Highly Cited
2010
The congenital dyserythropoietic anemias (CDAs) are inherited red blood cell disorders whose hallmarks are ineffective… (More)
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Highly Cited
2010
Highly Cited
2010
KLF1 regulates a diverse suite of genes to direct erythroid cell differentiation from bipotent progenitors. To determine the… (More)
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Highly Cited
2010
Highly Cited
2010
The c-myb transcription factor is highly expressed in immature hematopoietic cells and down-regulated during differentiation. To… (More)
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Review
2010
Review
2010
The molecular events and transcriptional mechanisms that underlie erythropoiesis are of great interest to biologists and… (More)
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Highly Cited
2008
Highly Cited
2008
Comparison of normal erythroblasts and erythroblasts from persons with the rare In(Lu) type of Lu(a-b-) blood group phenotype… (More)
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Highly Cited
2008
Highly Cited
2008
Transcription factors of the Sp/Klf (Krüppel-like factor) family regulate biological processes such as hematopoiesis… (More)
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