KIT wt Allele

Known as: SCFR, Stem Cell Factor Receptor Gene, CD117 
Human KIT wild-type allele is located within 4q11-q12 and is approximately 83 kb in length. This allele, which encodes mast/stem cell growth factor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
051020002017

Papers overview

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2016
2016
Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine… (More)
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2016
2016
Melanoma is an aggressive tumor with advanced disease characterized by widespread metastatic lesions and the tumor has… (More)
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2013
2013
Most gastrointestinal stromal tumors (GISTs) harbor oncogenic mutations in KIT or platelet-derived growth factor receptor… (More)
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2009
2009
10500 Background: Most gastrointestinal stromal tumors (GISTs) harbor mutant KIT or platelet-derived growth factor receptor alpha… (More)
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2009
2009
Gastrointestinal stromal tumours (GIST) are thought to derive from the interstitial cells of Cajal (ICC) or an ICC precursor… (More)
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2008
2008
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Activating… (More)
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Review
2005
Review
2005
The large majority of gastrointestinal stromal tumors (GIST) can be diagnosed on the basis of KIT immunoreactivity. However, some… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Mutated KIT and platelet-derived growth factor receptor alpha (PDGFRalpha) tyrosine kinases are the principal targets for… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND AND OBJECTIVES Mutations of KIT receptor tyrosine kinase are involved in the constitutive activation and development… (More)
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Highly Cited
2002
Highly Cited
2002
Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms of the gut wall that express the receptor tyrosine kinase KIT… (More)
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