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KIT wt Allele

Known as: SCFR, Stem Cell Factor Receptor Gene, CD117 
Human KIT wild-type allele is located within 4q11-q12 and is approximately 83 kb in length. This allele, which encodes mast/stem cell growth factor… 
National Institutes of Health

Related topics

Related topics

18 relations
4q11-q12C-KIT GeneGastrointestinal Stromal TumorsGerm cell tumor

Papers overview

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Highly Cited
2005
Highly Cited
2005
Human malignant melanoma: detection of BRAF- and c-kit-activating mutations by high-resolution amplicon melting analysis.
Highly Cited
2004
Highly Cited
2004
c-kit and PDGFRA Mutations in Extragastrointestinal Stromal Tumor (Gastrointestinal Stromal Tumor of the Soft Tissue)
Extragastrointestinal stromal tumor (EGIST) is a unique tumor that occurs outside the gastrointestinal tract. EGIST shows a c-kit… 
Highly Cited
2002
Highly Cited
2002
New insights into the pathogenesis of vitiligo: imbalance of epidermal cytokines at sites of lesions.
Vitiligo is a skin disease that is caused by selective destruction of melanocytes and is characterized by white spots… 
Highly Cited
2002
Highly Cited
2002
Differential sensitivity to imatinib of 2 patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans
Dermatofibrosarcoma protuberans (DFSP) is a rare superficial sarcoma usually affecting the trunk, with significant risk of local… 
Highly Cited
1998
Highly Cited
1998
A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors.
Highly Cited
1996
Highly Cited
1996
Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos.
In the mouse, the Kit receptor and its ligand, the stem cell factor (SCF), are encoded at the W/Kit and Steel loci, respectively… 
Highly Cited
1992
Highly Cited
1992
Localization of mRNA for c-kit receptor and its ligand in the brain of adult rats: an analysis using in situ hybridization histochemistry.
Highly Cited
1992
Highly Cited
1992
Expression of c-kit receptor in normal and transformed human nonlymphoid tissues.
The protooncogene c-kit encodes a tyrosine kinase with a molecular weight of 145,000, highly related to the platelet derived… 
Highly Cited
1991
Highly Cited
1991
Expression of c-kit encoded at the W locus of mice in developing embryonic germ cells and presumptive melanoblasts.
Highly Cited
1990
Highly Cited
1990
Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit
MICE carrying mutations at the W (Dominant white spotting) and SI (Steel) loci develop abnormalities in three independent systems… 
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